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Protein Ontology report - voltage-gated potassium channel KCND2 isoform 1
PR:000000947 -
http://purl.obolibrary.org/obo/PR_000000947
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000947
PRO name
voltage-gated potassium channel KCND2 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
KCND2/iso:1
Other
:
EXACT:
Kv4.2
Definition
"A voltage-gated potassium channel KCND2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q9NZV8-1
or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000785
voltage-gated potassium channel KCND2
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
5
Organism-Modification
6
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000000947
voltage-gated potassium channel KCND2 isoform 1, KCND2/iso:1
organism-sequence
PR:Q9NZV8-1
potassium voltage-gated channel subfamily D member 2 isoform 1 (human), hKCND2/iso:1
Yes
organism-sequence
PR:Q9Z0V2-1
potassium voltage-gated channel subfamily D member 2 isoform 1 (mouse), mKCND2/iso:1
Yes
organism-modification
PR:000036577
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 (mouse), mKCND2/iso:1/Phos:1
organism-modification
PR:000036578
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse), mKCND2/iso:1/Phos:2
Yes
organism-modification
PR:000036579
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse), mKCND2/iso:1/Phos:3
Yes
organism-modification
PR:000036580
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse), mKCND2/iso:1/Phos:4
Yes
organism-modification
PR:000045389
voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 3 (mouse), mKCND2/iso:1/UnPhos:3
Yes
organism-modification
PR:000045390
voltage-gated potassium channel KCND2 isoform 1 unphosphorylated 4 (mouse), mKCND2/iso:1/UnPhos:4
Yes
modification
PR:000000988
voltage-gated potassium channel KCND2 isoform 1 phosphorylated form, KCND2/iso:1/PhosRes+
modification
PR:000000994
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1, KCND2/iso:1/Phos:1
organism-modification
PR:000036577
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 1 (mouse), mKCND2/iso:1/Phos:1
modification
PR:000000995
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2, KCND2/iso:1/Phos:2
organism-modification
PR:000036578
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 (mouse), mKCND2/iso:1/Phos:2
Yes
modification
PR:000000996
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3, KCND2/iso:1/Phos:3
organism-modification
PR:000036579
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 (mouse), mKCND2/iso:1/Phos:3
Yes
modification
PR:000000997
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4, KCND2/iso:1/Phos:4
organism-modification
PR:000036580
voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 (mouse), mKCND2/iso:1/Phos:4
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036578
mKCND2/iso:1/Phos:2
UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047
"A voltage-gated potassium channel KCND2 isoform 1 phosphorylated 2 in mouse. UniProtKB:Q9Z0V2-1, Thr-38, MOD:00047." [PMID:11040264, PRO:CNA]
located_in
GO:0030425
dendrite
PMID:11040264
PR:000036579
mKCND2/iso:1/Phos:3
UniProtKB:Q9Z0V2-1, Ser-552, MOD:00046
"A voltage-gated potassium channel KCND2 isoform 1 phosphorylated 3 in mouse. UniProtKB:Q9Z0V2-1, Ser-552, MOD:00046." [PMID:11040264, PRO:CNA]
located_in
GO:0030425
dendrite
PMID:11040264
PR:000036580
mKCND2/iso:1/Phos:4
UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046
"A voltage-gated potassium channel KCND2 isoform 1 phosphorylated 4 in mouse. UniProtKB:Q9Z0V2-1, Thr-602/Thr-607, MOD:00047|Ser-616, MOD:00046." [PMID:11040264, PMID:16251476, PRO:CNA]
enables
decreased|contributes_to
GO:0005250
A-type (transient outward) potassium channel activity
relative to
PR:000002656
PMID:16251476
located_in
GO:0009986
cell surface
PMID:16251476
GO:0030425
dendrite
PMID:11040264
PR:000045389
mKCND2/iso:1/UnPhos:3
UniProtKB:Q9Z0V2-1, Ser-552, PR:000026291
"A potassium voltage-gated channel subfamily D member 2 isoform 1 (mouse) that lacks phosphorylation on Ser-552. UniProtKB:Q9Z0V2-1, Ser-552, PR:000026291." [PMID:12829703, PRO:CNA]
located_in
GO:0009986
cell surface
PMID:12829703
;
PMID:16251476
PR:000045390
mKCND2/iso:1/UnPhos:4
UniProtKB:Q9Z0V2-1, Thr-602/Thr-607/Ser-616, PR:000026291
"A potassium voltage-gated channel subfamily D member 2 isoform 1 (mouse) that lacks phosphorylation on Thr-602, Thr-607, and Ser-616. UniProtKB:Q9Z0V2-1, Thr-602/Thr-607/Ser-616, PR:000026291." [PMID:16251476, PRO:CNA]
enables
contributes_to
GO:0005250
A-type (transient outward) potassium channel activity
PMID:16251476
PR:Q9NZV8-1
hKCND2/iso:1
"A voltage-gated potassium channel KCND2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
acts_upstream_of_or_within
GO:0001508
action potential
PMID:11102480
GO:0007268
chemical synaptic transmission
PMID:11102480
located_in
GO:0009986
cell surface
PMID:12493773
PR:Q9Z0V2-1
mKCND2/iso:1
"A voltage-gated potassium channel KCND2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
located_in
GO:0005783
endoplasmic reticulum
PMID:12829703
