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Protein Ontology report - voltage-gated potassium channel KCNH2 isoform A
PR:000000957 - http://purl.obolibrary.org/obo/PR_000000957
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000957   
  PRO namevoltage-gated potassium channel KCNH2 isoform A 
  Synonyms
PRO-Short-label: EXACT:KCNH2/iso:A
Other: EXACT:voltage-gated potassium channel KCNH2 isoform 1
  Definition"A voltage-gated potassium channel KCNH2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12809-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000791 voltage-gated potassium channel KCNH2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification6                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000957 voltage-gated potassium channel KCNH2 isoform A, KCNH2/iso:A

organism-sequence


PR:O35219-1 potassium voltage-gated channel subfamily H member 2 isoform A (mouse), mKCNH2/iso:A
Yes
organism-modification


PR:000036582 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (mouse), mKCNH2/iso:A/NGlyco:1
Yes
organism-sequence


PR:Q12809-1 potassium voltage-gated channel subfamily H member 2 isoform A (human), hKCNH2/iso:A
Yes
organism-modification


PR:000036581 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (human), hKCNH2/iso:A/NGlyco:1
Yes
organism-modification


PR:000036583 voltage-gated potassium channel KCNH2 isoform A phosphorylated 1 (human), hKCNH2/iso:A/Phos:1
Yes
organism-modification


PR:000045392 voltage-gated potassium channel KCNH2 isoform A unglycosylated 1 (human), hKCNH2/iso:A/UnGlyco:1
Yes
organism-modification


PR:000045393 voltage-gated potassium channel KCNH2 isoform A unphosphorylated form (human), hKCNH2/iso:A/PhosRes-
Yes
modification


PR:000000989 voltage-gated potassium channel KCNH2 isoform A glycosylated form, KCNH2/iso:A/GlycoRes+

modification


PR:000000998 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1, KCNH2/iso:A/NGlyco:1

organism-modification


PR:000036581 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (human), hKCNH2/iso:A/NGlyco:1
Yes
organism-modification


PR:000036582 voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 (mouse), mKCNH2/iso:A/NGlyco:1
Yes
modification


PR:000000990 voltage-gated potassium channel KCNH2 isoform A phosphorylated form, KCNH2/iso:A/PhosRes+

modification


PR:000000999 voltage-gated potassium channel KCNH2 isoform A phosphorylated 1, KCNH2/iso:A/Phos:1

organism-modification


PR:000036583 voltage-gated potassium channel KCNH2 isoform A phosphorylated 1 (human), hKCNH2/iso:A/Phos:1
Yes
modification


PR:000002666 voltage-gated potassium channel KCNH2 isoform A unmodified form, KCNH2/iso:A/UnMod

modification


PR:000045391 voltage-gated potassium channel KCNH2 isoform A unglycosylated 1, KCNH2/iso:A/UnGlyco:1

organism-modification


PR:000045392 voltage-gated potassium channel KCNH2 isoform A unglycosylated 1 (human), hKCNH2/iso:A/UnGlyco:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036581 hKCNH2/iso:A/NGlyco:1
UniProtKB:Q12809-1, Asn-598, MOD:00160 | hKCNH2/iso:1/Glyco:1 | voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (human)
"A voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 in human. UniProtKB:Q12809-1, Asn-598, MOD:00160." [PMID:12063277, PRO:CNA]		 located_inGO:0008076 voltage-gated potassium channel complex PMID:12063277
GO:0009986 cell surface PMID:12063277
PR:000036582 mKCNH2/iso:A/NGlyco:1
UniProtKB:O35219-1, Asn-600, MOD:00160 | mKCNH2/iso:1/Glyco:1 | voltage-gated potassium channel KCNH2 isoform 1 glycosylated 1 (mouse)
"A voltage-gated potassium channel KCNH2 isoform A N-glycosylated 1 in mouse. UniProtKB:O35219-1, Asn-600, MOD:00160." [PMID:14668215, PRO:CNA]		 located_inGO:0005886 plasma membrane MGI:3040012; PMID:14668215
PR:000036583 hKCNH2/iso:A/Phos:1
hKCNH2/iso:1/Phos:1 | voltage-gated potassium channel KCNH2 isoform 1 phosphorylated 1 (human)
"A voltage-gated potassium channel KCNH2 isoform A phosphorylated 1 in human." [PMID:10837251, PRO:CNA]		 enablesdecreased GO:0005251 delayed rectifier potassium channel activity relative to PR:000002666 KCNH2/iso:1/UnMod PMID:10837251
located_inGO:0008076 voltage-gated potassium channel complex PMID:10837251
PR:000045392 hKCNH2/iso:A/UnGlyco:1
UniProtKB:Q12809-1, Asn-598, PR:000026291
"A voltage-gated potassium channel KCNH2 isoform A unglycosylated 1 in human. UniProtKB:Q12809-1, Asn-598, PR:000026291." [PMID:12063277, PRO:CNA]		 located_inGO:0009986 cell surface PMID:12063277
PR:000045393 hKCNH2/iso:A/PhosRes-

"A potassium voltage-gated channel subfamily H member 2 isoform A (human) that lacks phosphorylated residues." [PMID:10837251, PRO:CNA]		 enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:10837251; PMID:9351446
PR:O35219-1 mKCNH2/iso:A
potassium voltage-gated channel subfamily H member 2 isoform 1 (mouse) | potassium voltage-gated channel subfamily H member 2 isoform 1A (mouse)
"A voltage-gated potassium channel KCNH2 isoform A that is encoded in the genome of mouse." [PRO:CNA]		 enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:9351446; PMID:9351462
located_inGO:0005635 nuclear envelope MGI:3040012; PMID:14668215
GO:0005635 nuclear envelope MGI:3040012; PMID:14668215
GO:0005737 cytoplasm MGI:3040012; PMID:14668215
GO:0005737 cytoplasm MGI:3040012; PMID:14668215
GO:0005886 plasma membrane MGI:3040012; PMID:14668215
GO:0008076 voltage-gated potassium channel complex PMID:9351462
PR:Q12809-1 hKCNH2/iso:A

"A voltage-gated potassium channel KCNH2 isoform A that is encoded in the genome of human." [PRO:CNA]		 enablesGO:0030552 cAMP binding PMID:10837251