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Protein Ontology report - voltage-gated potassium channel subunit KCNA5 isoform 1
PR:000000974 - http://purl.obolibrary.org/obo/PR_000000974
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000974   
  PRO namevoltage-gated potassium channel subunit KCNA5 isoform 1 
  Synonyms
PRO-Short-label: EXACT:KCNA5/iso:1
  Definition"A voltage-gated potassium channel subunit KCNA5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22460-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000812 voltage-gated potassium channel subunit KCNA5
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000974 voltage-gated potassium channel subunit KCNA5 isoform 1, KCNA5/iso:1

organism-sequence


PR:P22460-1 potassium voltage-gated channel subfamily A member 5 isoform 1 (human), hKCNA5/iso:1
Yes
organism-sequence


PR:000036568 potassium voltage-gated channel subfamily A member 5 isoform 1 sequence variant E375* (human), hKCNA5/iso:1/var:E375*
Yes
organism-sequence


PR:Q61762-1 potassium voltage-gated channel subfamily A member 5 isoform 1 (mouse), mKCNA5/iso:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036568 hKCNA5/iso:1/var:E375*
UniProtKB:P22460-1, 1-374
"A potassium voltage-gated channel subfamily A member 5 isoform 1 (human) that has a C-terminal truncation and thus lacks the S4-S6 voltage sensor, pore region and C terminus, but preserves the N terminus and S1-S3 transmembrane domains that secure tetrameric subunit assembly. UniProtKB:P22460-1, 1-374." [PMID:16772329, PRO:CNA]		 enablesNOT|contributes_to GO:0005251 delayed rectifier potassium channel activity PMID:16772329
PR:P22460-1 hKCNA5/iso:1

"A voltage-gated potassium channel subunit KCNA5 isoform 1 that is encoded in the genome of human." [PRO:CNA]		 enablescontributes_to GO:0005251 delayed rectifier potassium channel activity PMID:1986382
PR:Q61762-1 mKCNA5/iso:1

"A voltage-gated potassium channel subunit KCNA5 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006813 potassium ion transport MGI:63618; PMID:8226976
enablesGO:0005249 voltage-gated potassium channel activity MGI:63618; PMID:8226976
located_inGO:0005886 plasma membrane MGI:63618; PMID:8226976