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Protein Ontology report - voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1
PR:000000992 -
http://purl.obolibrary.org/obo/PR_000000992
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000992
PRO name
voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
KCNC1/iso:Long/Phos:1
Other
:
EXACT:
KCNC1/iso:2/Phos:1 | voltage-gated potassium channel KCNC1 isoform 2 phosphorylated 1
Definition
"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated form in which the phosphorylation occurs by the action of PKC at the Ser residue within the DSKL motif located in the C-terminal tail. In resting neurons, basal phosphorylation at this site decreases Kv3.1 channel current, reducing neuronal ability to follow high frequency stimulation. Example:
UniProtKB:P25122-1
, Ser-503,
MOD:00046
." [
PMID:16595659
]
PRO Category
modification
Parent
PR:000000986
voltage-gated potassium channel KCNC1 isoform Long phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000000992
voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1, KCNC1/iso:Long/Phos:1
organism-modification
PR:000036575
voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat), rKCNC1/iso:Long/Phos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036575
rKCNC1/iso:Long/Phos:1
UniProtKB:P25122-1, Ser-503, MOD:00046 | rKCNC1/iso:2/Phos:1 | voltage-gated potassium channel KCNC1 isoform 2 phosphorylated 1 (rat)
"A voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 in rat. UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659, PRO:CNA]
enables
decreased|contributes_to
GO:0005249
voltage-gated potassium channel activity
relative to
PR:000002649
PMID:16595659
located_in
GO:0016020
membrane
PMID:16595659