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Protein Ontology report - voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1
PR:000001000 -
http://purl.obolibrary.org/obo/PR_000001000
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000001000
PRO name
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
KCNA2/iso:1/Phos:1
Definition
"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residue within the REDEGYIK sequence located adjacent to the tetramerization domain. Phosphorylation at this site promotes endocytosis and suppresses the channel activity. Example:
UniProtKB:P16389-1
, Tyr-132,
MOD:00048
." [PRO:CNA]
PRO Category
modification
Parent
PR:000000991
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000001000
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1, KCNA2/iso:1/Phos:1
organism-modification
PR:000036584
voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 (human), hKCNA2/iso:1/Phos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036584
hKCNA2/iso:1/Phos:1
UniProtKB:P16389-1, Tyr-132, MOD:00048
"A voltage-gated potassium channel subunit KCNA2 isoform 1 phosphorylated 1 in human. UniProtKB:P16389-1, Tyr-132, MOD:00048." [PMID:15215309, PRO:CNA]
enables
NOT
GO:0005251
delayed rectifier potassium channel activity
PMID:15215309
located_in
GO:0005768
endosome
PMID:15215309
