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Protein Ontology report - T-cell surface glycoprotein CD3
PR:000001027 - http://purl.obolibrary.org/obo/PR_000001027
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001027   
  PRO nameT-cell surface glycoprotein CD3 
  Synonyms
PRO-Short-label: EXACT:CD247
Gene-based: RELATED:CD3Z | T3Z | TCRZ
Other: EXACT:T-cell receptor T3 eta chain | T-cell receptor T3 zeta chain
  Definition"A protein that is a translation product of the human CD247 gene or a 1:1 ortholog thereof. It consists of an extracellular short N-terminal domain, a transmembrane domain, and an intracellular C-terminal domain with two to three copies of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM)." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 5                                        
         Modification5                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF028738
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001027 T-cell surface glycoprotein CD3, CD247

organism-gene


PR:P20963 T-cell surface glycoprotein CD3 (human), hCD247

organism-sequence


PR:P20963-1 T-cell surface glycoprotein CD3 zeta chain (human), hCD247/iso:CD3 zeta

organism-modification


PR:000036628 T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1 (human), hCD247/iso:CD3 zeta/Phos:1
Yes
organism-modification


PR:000061848 T-cell surface glycoprotein CD3 zeta chain, signal peptide removed form (human), hCD247/iso:CD3 zeta/SigPep-

organism-modification


PR:000063475 T-cell surface glycoprotein CD3 zeta chain, signal peptide removed phosphorylated 1 (human), hCD247/iso:CD3 zeta/SigPep-/Phos:1

organism-sequence


PR:P20963-2 T-cell surface glycoprotein CD3 eta chain (human), hCD247/iso:CD3 eta

organism-sequence


PR:P20963-3 T-cell surface glycoprotein CD3 isoform 3 (human), hCD247/iso:3

organism-gene


PR:P24161 T-cell surface glycoprotein CD3 isoforms eta/zeta (mouse), mCD247

organism-sequence


PR:P24161-1 T-cell surface glycoprotein CD3 zeta chain (mouse), mCD247/iso:CD3 zeta

organism-sequence


PR:P24161-2 T-cell surface glycoprotein CD3 eta (mouse), mCD247/iso:CD3 eta

sequence


PR:000001028 T-cell surface glycoprotein CD3 isoform CD3 eta, CD247/iso:CD3 eta

organism-sequence


PR:P24161-2 T-cell surface glycoprotein CD3 eta (mouse), mCD247/iso:CD3 eta

modification


PR:000026667 T-cell surface glycoprotein CD3 isoform CD3 eta, signal peptide removed form, CD247/iso:CD3 eta/SigPep-

sequence


PR:000001029 T-cell surface glycoprotein CD3 isoform CD3 zeta, CD247/iso:CD3 zeta

organism-sequence


PR:P20963-1 T-cell surface glycoprotein CD3 zeta chain (human), hCD247/iso:CD3 zeta

organism-modification


PR:000036628 T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1 (human), hCD247/iso:CD3 zeta/Phos:1
Yes
organism-modification


PR:000061848 T-cell surface glycoprotein CD3 zeta chain, signal peptide removed form (human), hCD247/iso:CD3 zeta/SigPep-

organism-modification


PR:000063475 T-cell surface glycoprotein CD3 zeta chain, signal peptide removed phosphorylated 1 (human), hCD247/iso:CD3 zeta/SigPep-/Phos:1

organism-sequence


PR:P24161-1 T-cell surface glycoprotein CD3 zeta chain (mouse), mCD247/iso:CD3 zeta

modification


PR:000003061 T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated form, CD247/iso:CD3 zeta/PhosRes+

modification


PR:000003062 T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1, CD247/iso:CD3 zeta/Phos:1

organism-modification


PR:000036628 T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1 (human), hCD247/iso:CD3 zeta/Phos:1
Yes
organism-modification


PR:000063475 T-cell surface glycoprotein CD3 zeta chain, signal peptide removed phosphorylated 1 (human), hCD247/iso:CD3 zeta/SigPep-/Phos:1

modification


PR:000026560 T-cell surface glycoprotein CD3 isoform CD3 zeta, signal peptide removed form, CD247/iso:CD3 zeta/SigPep-

modification


PR:000018329 T-cell surface glycoprotein CD3, signal peptide removed form, CD247/SigPep-

modification


PR:000026560 T-cell surface glycoprotein CD3 isoform CD3 zeta, signal peptide removed form, CD247/iso:CD3 zeta/SigPep-

modification


PR:000026667 T-cell surface glycoprotein CD3 isoform CD3 eta, signal peptide removed form, CD247/iso:CD3 eta/SigPep-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036628
hCD247/iso:CD3 zeta/Phos:1
 acts_upstream_of_or_withinGO:0050852 T cell receptor signaling pathway PMID:9043947
located_inGO:0005886 plasma membrane PMID:9043947