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Protein Ontology report - interleukin-1 alpha
PR:000001135 - http://purl.obolibrary.org/obo/PR_000001135
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001135   
  PRO nameinterleukin-1 alpha 
  Synonyms
PRO-Short-label: EXACT:IL1A
Gene-based: RELATED:IL1F1
Other: EXACT:hematopoietin-1 | IL-1 alpha
  Definition"An interleukin-1 that is a translation product of the human IL1A gene or a 1:1 ortholog thereof. Critical mediator of the immune and inflammatory responses." [PRO:CNA, Wikipedia:Interleukin_1] 
  PRO Categorygene 
  ParentPR:000001091
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification7                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001135 interleukin-1 alpha, IL1A

organism-gene


PR:P01582 interleukin-1 alpha (mouse), mIL1A

organism-sequence


PR:P01582-1 interleukin-1 alpha isoform 1 (mouse), mIL1A/iso:1

organism-modification


PR:000036600 interleukin-1 alpha isoform 1 phosphorylated 1 (mouse), mIL1A/iso:1/Phos:1
Yes
organism-modification


PR:000045524 interleukin-1 alpha isoform 1 cleaved 1 (mouse), mIL1A/iso:1/Clv:1

organism-modification


PR:000045525 interleukin-1 alpha isoform 1 precursor (mouse), mIl1a/iso:1/Full

organism-gene


PR:P01583 interleukin-1 alpha (human), hIL1A

organism-sequence


PR:P01583-1 interleukin-1 alpha isoform 1 (human), hIL1A/iso:1

organism-modification


PR:000036597 interleukin-1 alpha isoform 1 cleaved 1 (human), hIL1A/iso:1/Clv:1
Yes
organism-modification


PR:000036598 interleukin-1 alpha isoform 1 myristoylated 1 (human), hIL1A/iso:1/Myr:1
Yes
organism-modification


PR:000036599 interleukin-1 alpha isoform 1 myristoylated 2 (human), hIL1A/iso:1/Myr:2
Yes
organism-gene


PR:P16598 interleukin-1 alpha (rat), rIL1A

sequence


PR:000001227 interleukin-1 alpha isoform 1, IL1A/iso:1

organism-sequence


PR:P01582-1 interleukin-1 alpha isoform 1 (mouse), mIL1A/iso:1

organism-modification


PR:000036600 interleukin-1 alpha isoform 1 phosphorylated 1 (mouse), mIL1A/iso:1/Phos:1
Yes
organism-modification


PR:000045524 interleukin-1 alpha isoform 1 cleaved 1 (mouse), mIL1A/iso:1/Clv:1

organism-modification


PR:000045525 interleukin-1 alpha isoform 1 precursor (mouse), mIl1a/iso:1/Full

organism-sequence


PR:P01583-1 interleukin-1 alpha isoform 1 (human), hIL1A/iso:1

organism-modification


PR:000036597 interleukin-1 alpha isoform 1 cleaved 1 (human), hIL1A/iso:1/Clv:1
Yes
organism-modification


PR:000036598 interleukin-1 alpha isoform 1 myristoylated 1 (human), hIL1A/iso:1/Myr:1
Yes
organism-modification


PR:000036599 interleukin-1 alpha isoform 1 myristoylated 2 (human), hIL1A/iso:1/Myr:2
Yes
modification


PR:000001259 interleukin-1 alpha isoform 1 myristoylated form, IL1A/iso:1/MyrRes+

modification


PR:000001268 interleukin-1 alpha isoform 1 myristoylated 1, IL1A/iso:1/Myr:1

organism-modification


PR:000036598 interleukin-1 alpha isoform 1 myristoylated 1 (human), hIL1A/iso:1/Myr:1
Yes
modification


PR:000001269 interleukin-1 alpha isoform 1 myristoylated 2, IL1A/iso:1/Myr:2

organism-modification


PR:000036599 interleukin-1 alpha isoform 1 myristoylated 2 (human), hIL1A/iso:1/Myr:2
Yes
modification


PR:000001260 interleukin-1 alpha isoform 1 phosphorylated form, IL1A/iso:1/PhosRes+

modification


PR:000001270 interleukin-1 alpha isoform 1 phosphorylated 1, IL1A/iso:1/Phos:1

organism-modification


PR:000036600 interleukin-1 alpha isoform 1 phosphorylated 1 (mouse), mIL1A/iso:1/Phos:1
Yes
modification


PR:000001267 interleukin-1 alpha isoform 1 cleaved 1, IL1A/iso:1/Clv:1

organism-modification


PR:000036597 interleukin-1 alpha isoform 1 cleaved 1 (human), hIL1A/iso:1/Clv:1
Yes
organism-modification


PR:000045524 interleukin-1 alpha isoform 1 cleaved 1 (mouse), mIL1A/iso:1/Clv:1

modification


PR:000018344 interleukin-1 alpha proteolytic cleavage product, IL1A/ClvPrd

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036597
hIL1A/iso:1/Clv:1
UniProtKB:P01583-1, 113-271 | PRO_0000015266		 located_inGO:0005615 extracellular space PMID:3281727
PR:000036598
hIL1A/iso:1/Myr:1
UniProtKB:P01583-1, Lys-83, MOD:00087		 located_inGO:0016020 membrane PMID:8346241
PR:000036599
hIL1A/iso:1/Myr:2
UniProtKB:P01583-1, Lys-82, MOD:00087		 located_inGO:0016020 membrane PMID:8346241
PR:000036600
mIL1A/iso:1/Phos:1
UniProtKB:P01582-1, Ser-90, MOD:00046		 located_inGO:0016020 membrane PMID:3126184