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Protein Ontology report - frizzled-like G-protein coupled receptor
PR:000001315 - http://purl.obolibrary.org/obo/PR_000001315
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001315   
  PRO namefrizzled-like G-protein coupled receptor 
  Synonyms
PRO-Short-label: EXACT:fam:frizzled
Other: EXACT:class F G-protein coupled receptor
  Definition"A G-protein coupled receptor with core architecture consisting of an Fz domain (Pfam:PF01392), also known as Frizzled CRD (cysteine rich domain), followed by a Frizzled/Smoothened family membrane region (Pfam:PF01534), which includes 7 transmembrane helices, and a cytoplasmic domain containing the motif Lys-Thr-x-x-x-Trp. They generally function as cell-surface receptors for Wnts." [InterPro:IPR015526, PRO:DAN, PRO:WCB] 
  CommentClassification based on GRAFS system. [PMID:12761335]. 
  PRO Categoryfamily 
  ParentPR:000030035
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene11                                                  Organism-Gene 36                                        
         Sequence4                                                  Organism-Sequence 12                                        
         Modification1                                                  Organism-Modification 34                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF006696;IUPHARfam:25
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001315 frizzled-like G-protein coupled receptor, fam:frizzled

gene


PR:000001453 frizzled-10, FZD10

organism-gene


PR:Q8BKG4 frizzled-10 (mouse), mFZD10

organism-gene


PR:Q9PWH2 frizzled-10 (chicken), chick-FZD10

organism-gene


PR:Q9ULW2 frizzled-10 (human), hFZD10

organism-modification


PR:000047470 frizzled-10, signal peptide removed form (human), hFZD10/SigPep-

gene


PR:000001454 frizzled-4, FZD4

organism-gene


PR:Q61088 frizzled-4 (mouse), mFZD4

organism-sequence


PR:Q61088-1 frizzled-4 isoform 1 (mouse), mFZD4/iso:1

organism-gene


PR:Q9IA05 frizzled-4 (chicken), chick-FZD4

organism-gene


PR:Q9QZH0 frizzled-4 (rat), rFZD4

organism-gene


PR:Q9ULV1 frizzled-4 (human), hFZD4

organism-sequence


PR:Q9ULV1-1 frizzled-4 isoform 1 (human), hFZD4/iso:1

organism-modification


PR:000047473 frizzled-4, signal peptide removed form (human), hFZD4/SigPep-

organism-modification


PR:000047474 frizzled-4, signal peptide removed ubiquitinated form (human), hFZD4/SigPep-/UbiqLys+

organism-modification


PR:000047474 frizzled-4, signal peptide removed ubiquitinated form (human), hFZD4/SigPep-/UbiqLys+

sequence


PR:000044007 frizzled-4 isoform 1, FZD4/iso:1

organism-sequence


PR:Q61088-1 frizzled-4 isoform 1 (mouse), mFZD4/iso:1

organism-sequence


PR:Q9ULV1-1 frizzled-4 isoform 1 (human), hFZD4/iso:1

gene


PR:000001455 frizzled-9, FZD9

organism-gene


PR:O00144 frizzled-9 (human), hFZD9

organism-modification


PR:000047481 frizzled-9, signal peptide removed form (human), hFZD9/SigPep-

organism-gene


PR:Q8K4C8 frizzled-9 (rat), rFZD9

organism-gene


PR:Q9R216 frizzled-9 (mouse), mFZD9

gene


PR:000007718 frizzled-1, FZD1

organism-gene


PR:O57328 frizzled-1 (chicken), chick-FZD1

organism-gene


PR:O70421 frizzled-1 (mouse), mFZD1

organism-gene


PR:Q08463 frizzled-1 (rat), rFZD1

organism-gene


PR:Q9UP38 frizzled-1 (human), hFZD1

organism-modification


PR:000047469 frizzled-1, signal peptide removed form (human), hFZD1/SigPep-

organism-modification


PR:000058343 frizzled-1 O-glycosylated 1 (human), hFZD1/OGlyco:1

organism-modification


PR:000058344 frizzled-1 O-glycosylated 2 (human), hFZD1/OGlyco:2

gene


PR:000007719 frizzled-2, FZD2

organism-gene


PR:Q08464 frizzled-2 (rat), rFZD2

organism-gene


PR:Q14332 frizzled-2 (human), hFZD2

organism-modification


PR:000047471 frizzled-2, signal peptide removed form (human), hFZD2/SigPep-

organism-modification


PR:000057124 frizzled-2 O-glycosylated 1 (human), hFZD2/OGlyco:1

organism-modification


PR:000057125 frizzled-2 O-glycosylated 2 (human), hFZD2/OGlyco:2

organism-gene


PR:Q9JIP6 frizzled-2 (mouse), mFZD2

gene


PR:000007720 frizzled-3, FZD3

organism-gene


PR:Q61086 frizzled-3 (mouse), mFZD3

organism-sequence


PR:Q61086-1 frizzled-3 isoform 1 (mouse), mFZD3/iso:1

organism-modification


PR:000076795 frizzled-3 cysteinylated 1 (mouse), mFZD3/Cyst:1

organism-gene


PR:Q9NPG1 frizzled-3 (human), hFZD3

organism-sequence


PR:Q9NPG1-1 frizzled-3 isoform Long (human), hFZD3/iso:Long

organism-sequence


PR:Q9NPG1-2 frizzled-3 isoform Short (human), hFZD3/iso:Short

organism-modification


PR:000047472 frizzled-3, signal peptide removed form (human), hFZD3/SigPep-

sequence


PR:000043476 frizzled-3 isoform 1, FZD3/iso:1

organism-sequence


PR:Q61086-1 frizzled-3 isoform 1 (mouse), mFZD3/iso:1

organism-sequence


PR:Q9NPG1-1 frizzled-3 isoform Long (human), hFZD3/iso:Long

modification


PR:000019950 frizzled-3, signal peptide removed form, FZD3/SigPep-

organism-modification


PR:000047472 frizzled-3, signal peptide removed form (human), hFZD3/SigPep-

gene


PR:000007721 frizzled-5, FZD5

organism-gene


PR:Q13467 frizzled-5 (human), hFZD5

organism-sequence


PR:Q13467-1 frizzled-5 isoform 1 (human), hFZD5/iso:1

organism-modification


PR:000047475 frizzled-5, signal peptide removed form (human), hFZD5/SigPep-

organism-modification


PR:000047476 frizzled-5, signal peptide removed ubiquitinated form (human), hFZD5/SigPep-/UbiqLys+

organism-modification


PR:000047476 frizzled-5, signal peptide removed ubiquitinated form (human), hFZD5/SigPep-/UbiqLys+

organism-modification


PR:000057033 frizzled-5 O-glycosylated 1 (human), hFZD5/OGlyco:1

organism-gene


PR:Q1ZXI9 frizzled and smoothened-like protein O (Dictyostelium discoideum), Dicty-FZD5

organism-gene


PR:Q8CHL0 frizzled-5 (rat), rFZD5

organism-sequence


PR:Q8CHL0-1 frizzled-5 isoform 1 (rat), rFZD5/iso:1

organism-gene


PR:Q9EQD0 frizzled-5 (mouse), mFZD5

organism-sequence


PR:Q9EQD0-1 frizzled-5 isoform 1 (mouse), mFZD5/iso:1

sequence


PR:000040435 frizzled-5 isoform 1, FZD5/iso:1

organism-sequence


PR:Q13467-1 frizzled-5 isoform 1 (human), hFZD5/iso:1

organism-sequence


PR:Q8CHL0-1 frizzled-5 isoform 1 (rat), rFZD5/iso:1

organism-sequence


PR:Q9EQD0-1 frizzled-5 isoform 1 (mouse), mFZD5/iso:1

gene


PR:000007722 frizzled-6, FZD6

organism-gene


PR:O60353 frizzled-6 (human), hFZD6

organism-sequence


PR:O60353-1 frizzled-6 isoform h1 (human), hFZD6/iso:h1

organism-sequence


PR:O60353-2 frizzled-6 isoform h2 (human), hFZD6/iso:h2

organism-modification


PR:000047477 frizzled-6, signal peptide removed ubiquitinated form (human), hFZD6/SigPep-/UbiqLys+

organism-modification


PR:000050771 frizzled-6 N-glycosylated 1 (human), hFZD6/NGlyco:1

organism-modification


PR:000050772 frizzled-6 N-glycosylated 2 (human), hFZD6/NGlyco:2

organism-modification


PR:000050773 frizzled-6 O-glycosylated 1 (human), hFZD6/OGlyco:1

organism-modification


PR:000050774 frizzled-6 O-glycosylated 2 (human), hFZD6/OGlyco:2

organism-modification


PR:000063743 frizzled-6, signal peptide removed form (human), hFZD6/SigPep-

organism-modification


PR:000066533 frizzled-6 cysteinylated 1 (human), hFZD6/Cyst:1

organism-modification


PR:000080579 frizzled-6 deaminated 1 (human), hFZD6/Deam:1

organism-gene


PR:Q61089 frizzled-6 (mouse), mFZD6

gene


PR:000007723 frizzled-7, FZD7

organism-gene


PR:O57329 frizzled-7 (chicken), chick-FZD7

organism-gene


PR:O75084 frizzled-7 (human), hFZD7

organism-modification


PR:000047478 frizzled-7, signal peptide removed form (human), hFZD7/SigPep-

organism-modification


PR:000050815 frizzled-7 O-glycosylated 1 (human), hFZD7/OGlyco:1

organism-gene


PR:Q61090 frizzled-7 (mouse), mFZD7

organism-modification


PR:000068087 frizzled-7 cysteinylated 1 (mouse), mFZD7/Cyst:1

gene


PR:000007724 frizzled-8, FZD8

organism-gene


PR:Q498S8 frizzled-8 (rat), rFZD8

organism-gene


PR:Q61091 frizzled-8 (mouse), mFZD8

organism-gene


PR:Q9H461 frizzled-8 (human), hFZD8

organism-modification


PR:000047479 frizzled-8, signal peptide removed form (human), hFZD8/SigPep-

organism-modification


PR:000047480 frizzled-8, signal peptide removed ubiquitinated form (human), hFZD8/SigPep-/UbiqLys+

organism-modification


PR:000047480 frizzled-8, signal peptide removed ubiquitinated form (human), hFZD8/SigPep-/UbiqLys+

gene


PR:000015288 protein smoothened, SMO

organism-gene


PR:P56726 protein smoothened (mouse), mSMO

organism-sequence


PR:P56726-1 protein smoothened isoform 1 (mouse), mSMO/iso:1

organism-gene


PR:P91682 protein smoothened (fruit fly), fly-SMO

organism-gene


PR:P97698 protein smoothened (rat), rSMO

organism-sequence


PR:P97698-1 protein smoothened isoform 1 (rat), rSMO/iso:1

organism-gene


PR:Q5RH73 protein smoothened (zebrafish), z-SMO

organism-gene


PR:Q99835 protein smoothened (human), hSMO

organism-modification


PR:000049297 protein smoothened, signal peptide removed form (human), hSMO/SigPep-

organism-modification


PR:000049298 protein smoothened, signal peptide removed phosphorylated 1 (human), hSMO/SigPep-/Phos:1

organism-modification


PR:000049299 protein smoothened, signal peptide removed phosphorylated 2 (human), hSMO/SigPep-/Phos:2

organism-modification


PR:000057979 protein smoothened N-glycosylated 1 (human), hSMO/NGlyco:1

organism-modification


PR:000057980 protein smoothened O-glycosylated 1 (human), hSMO/OGlyco:1

organism-modification


PR:000057981 protein smoothened O-glycosylated 2 (human), hSMO/OGlyco:2

sequence


PR:000039833 protein smoothened isoform 1, SMO/iso:1

organism-sequence


PR:P56726-1 protein smoothened isoform 1 (mouse), mSMO/iso:1

organism-sequence


PR:P97698-1 protein smoothened isoform 1 (rat), rSMO/iso:1