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Protein Ontology report - proteinase-activated receptor 1
PR:000001661 - http://purl.obolibrary.org/obo/PR_000001661
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001661   
  PRO nameproteinase-activated receptor 1 
  Synonyms
PRO-Short-label: EXACT:F2R
Gene-based: RELATED:CF2R | PAR1 | TR
Other: EXACT:coagulation factor II receptor | PAR-1 | thrombin receptor
  Definition"A proteinase-activated receptor that is a translation product of the human F2R gene or a 1:1 ortholog thereof. It is activated by thrombin, which cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity." [PMID:1672265, PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001550
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:347
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001661 proteinase-activated receptor 1, F2R


organism-gene



PR:P25116 proteinase-activated receptor 1 (human), hF2R


organism-modification



PR:000060708 proteinase-activated receptor 1, signal peptide removed form (human), hF2R/SigPep-


organism-modification



PR:000073448 proteinase-activated receptor 1 deaminated 1 (human), hF2R/Deam:1


organism-gene



PR:P26824 proteinase-activated receptor 1 (rat), rF2R


organism-gene



PR:P30558 proteinase-activated receptor 1 (mouse), mF2R


modification



PR:000018513 proteinase-activated receptor 1 proteolytic cleavage product, F2R/ClvPrd