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RACE-PRO
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Protein Ontology report - proteinase-activated receptor 1
PR:000001661 -
http://purl.obolibrary.org/obo/PR_000001661
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000001661
PRO name
proteinase-activated receptor 1
Synonyms
PRO-Short-label
:
EXACT:
F2R
Gene-based
:
RELATED:
CF2R | PAR1 | TR
Other
:
EXACT:
coagulation factor II receptor | PAR-1 | thrombin receptor
Definition
"A proteinase-activated receptor that is a translation product of the human F2R gene or a 1:1 ortholog thereof. It is activated by thrombin, which cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity." [
PMID:1672265
, PRO:WCB]
PRO Category
gene
Parent
PR:000001550
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
1
Organism-Gene
3
Sequence
0
Organism-Sequence
0
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
IUPHARobj:347
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
gene
PR:000001661
proteinase-activated receptor 1, F2R
organism-gene
PR:P25116
proteinase-activated receptor 1 (human), hF2R
organism-modification
PR:000060708
proteinase-activated receptor 1, signal peptide removed form (human), hF2R/SigPep-
organism-modification
PR:000073448
proteinase-activated receptor 1 deaminated 1 (human), hF2R/Deam:1
organism-gene
PR:P26824
proteinase-activated receptor 1 (rat), rF2R
organism-gene
PR:P30558
proteinase-activated receptor 1 (mouse), mF2R
modification
PR:000018513
proteinase-activated receptor 1 proteolytic cleavage product, F2R/ClvPrd