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Protein Ontology report - nuclear factor NF-kappa-B p50 subunit
PR:000001757 - http://purl.obolibrary.org/obo/PR_000001757
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001757   
  PRO namenuclear factor NF-kappa-B p50 subunit 
  Synonyms
PRO-Short-label: EXACT:NFKBp50
Other: EXACT:NF-KAPPA-B P50 | NFKB1 p50 | nuclear factor NF-kappa-B p105 subunit isoform 1 cleaved 1
  Definition"A nuclear factor NF-kappa-B p105 subunit isoform 1 that has been processed by proteolytic cleavage to remove the C-terminal domain of p105 downstream from the 23-residue glycine rich region (GRR). Example: UniProtKB:P19838-1, 1-433." [PMID:2203532, PMID:8628291, PRO:DAN, PRO:JAN] 
  CommentNote: GRR functions as a processing signal for the generation of the p50 subunit. 
  PRO Categorymodification 
  ParentPR:000001755 nuclear factor NF-kappa-B p105 subunit isoform 1
PR:000018519 nuclear factor NF-kappa-B p105 subunit proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000001757 nuclear factor NF-kappa-B p50 subunit, NFKBp50

organism-modification


PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse), mNFKBp50

Yes
organism-modification


PR:000035834 nuclear factor NF-kappa-B p50 subunit (human), hNFKBp50
Yes
Yes
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NFKBp50 forms found in complexes   

NFKBp50 Component
 Complexes
PR:000028540 mNFKBp50 PR:000028542 NF-kappaB p50/p65 complex (mouse)
PR:000035834 hNFKBp50 PR:000035835 NF-kappaB p50/p65 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035834 hNFKBp50
UniProtKB:P19838, 1-433 | UniProtKB:P19838-1, 1-433 | NF-KAPPA-B P50 (human) | NFKB1 p50 (human) | PRO_0000030311 | p50 (human) (BROAD)
"A nuclear factor NF-kappa-B p50 subunit in human. Example: UniProtKB:P19838-1, 1-433." [PRO:DNx, UniProtKB:P19838]		 acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894