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Protein Ontology report - MHC class II histocompatibility antigen alpha chain
PR:000001820 - http://purl.obolibrary.org/obo/PR_000001820
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001820   
  PRO nameMHC class II histocompatibility antigen alpha chain 
  Synonyms
PRO-Short-label: EXACT:MHCcIIalpha
  Definition"A protein with core architecture consisting of a signal sequence, a Class II histocompatibility antigen, alpha domain (Pfam:PF00993) and an Immunoglobulin C1-set domain (Pfam:PF07654); these form the extracellular domain and are followed by a single-pass transmembrane region and a small cytoplasmic region." [PRO:WCB, Wikipedia:Human_leukocyte_antigen] 
  CommentNote: There are three major and two minor class II MHC (major histocompatability complex) alpha chain genes in human. Designations for the MHC complex loci are species specific: HLA (human leukocyte antigen) in human, H-2 in mouse. MHC class II loci are characterized by large numbers of allelic variants. In contrast to MHC Class I alpha chain genes, orthologies can be seen between some human and mouse genes. MHC class II alpha chains form heterodimers with MHLC class II beta chains. 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene6                                                  Organism-Gene 10                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification4                                                  Organism-Modification 49                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001820 MHC class II histocompatibility antigen alpha chain, MHCcIIalpha

gene


PR:000002012 MHC class II histocompatibility antigen alpha chain DPA1, MHCcIIalpha_DPA1

organism-gene


PR:P20036 HLA class II histocompatibility antigen, DP alpha 1 chain (human), hHLA-DPA1

organism-modification


PR:000064372 HLA class II histocompatibility antigen, DP alpha 1 chain, signal peptide removed form (human), hHLA-DPA1/SigPep-

organism-modification


PR:000065671 HLA class II histocompatibility antigen, DP alpha 1 chain deaminated 1 (human), hHLA-DPA1/Deam:1

organism-modification


PR:000066175 HLA class II histocompatibility antigen, DP alpha 1 chain deaminated 2 (human), hHLA-DPA1/Deam:2

organism-modification


PR:000070324 HLA class II histocompatibility antigen, DP alpha 1 chain methylated 1 (human), hHLA-DPA1/Me:1

organism-modification


PR:000072443 HLA class II histocompatibility antigen, DP alpha 1 chain methylated 2 (human), hHLA-DPA1/Me:2

organism-modification


PR:000073534 HLA class II histocompatibility antigen, DP alpha 1 chain methylated 3 (human), hHLA-DPA1/Me:3

organism-modification


PR:000074013 HLA class II histocompatibility antigen, DP alpha 1 chain deaminated 3 (human), hHLA-DPA1/Deam:3

organism-modification


PR:000074917 HLA class II histocompatibility antigen, DP alpha 1 chain methylated 4 (human), hHLA-DPA1/Me:4

organism-modification


PR:000074992 HLA class II histocompatibility antigen, DP alpha 1 chain deaminated 4 (human), hHLA-DPA1/Deam:4

organism-modification


PR:000075998 HLA class II histocompatibility antigen, DP alpha 1 chain deaminated 5 (human), hHLA-DPA1/Deam:5

organism-modification


PR:000077190 HLA class II histocompatibility antigen, DP alpha 1 chain deaminated 6 (human), hHLA-DPA1/Deam:6

organism-modification


PR:000080248 HLA class II histocompatibility antigen, DP alpha 1 chain formylated 1 (human), hHLA-DPA1/Form:1

organism-modification


PR:000083097 HLA class II histocompatibility antigen, DP alpha 1 chain deaminated 7 (human), hHLA-DPA1/Deam:7

modification


PR:000018672 MHC class II histocompatibility antigen alpha chain DPA1, signal peptide removed form, MHCcIIalpha_DPA1/SigPep-

gene


PR:000002013 MHC class II histocompatibility antigen alpha chain DQA1, MHCcIIalpha_DQA1

organism-gene


PR:P01909 HLA class II histocompatibility antigen, DQ alpha 1 chain (human), hHLA-DQA1

organism-modification


PR:000061371 HLA class II histocompatibility antigen, DQ alpha 1 chain, signal peptide removed form (human), hHLA-DQA1/SigPep-

organism-modification


PR:000066521 HLA class II histocompatibility antigen, DQ alpha 1 chain deaminated 1 (human), hHLA-DQA1/Deam:1

organism-modification


PR:000074305 HLA class II histocompatibility antigen, DQ alpha 1 chain cysteinylated 1 (human), hHLA-DQA1/Cyst:1

organism-modification


PR:000076246 HLA class II histocompatibility antigen, DQ alpha 1 chain methylated 1 (human), hHLA-DQA1/Me:1

organism-modification


PR:000076909 HLA class II histocompatibility antigen, DQ alpha 1 chain deaminated 2 (human), hHLA-DQA1/Deam:2

organism-modification


PR:000077370 HLA class II histocompatibility antigen, DQ alpha 1 chain deaminated 3 (human), hHLA-DQA1/Deam:3

organism-modification


PR:000084065 HLA class II histocompatibility antigen, DQ alpha 1 chain deaminated 4 (human), hHLA-DQA1/Deam:4

organism-gene


PR:P20037 Rano class II histocompatibility antigen, B alpha chain (rat), rRT1-Ba

modification


PR:000018674 MHC class II histocompatibility antigen alpha chain DQA1, signal peptide removed form, MHCcIIalpha_DQA1/SigPep-

gene


PR:000002014 MHC class II histocompatibility antigen alpha chain DQA2, MHCcIIalpha_DQA2

organism-gene


PR:P01906 HLA class II histocompatibility antigen, DQ alpha 2 chain (human), hHLA-DQA2

organism-modification


PR:000062243 HLA class II histocompatibility antigen, DQ alpha 2 chain, signal peptide removed form (human), hHLA-DQA2/SigPep-

organism-modification


PR:000067927 HLA class II histocompatibility antigen, DQ alpha 2 chain methylated 1 (human), hHLA-DQA2/Me:1

organism-modification


PR:000069625 HLA class II histocompatibility antigen, DQ alpha 2 chain cysteinylated 1 (human), hHLA-DQA2/Cyst:1

organism-modification


PR:000070272 HLA class II histocompatibility antigen, DQ alpha 2 chain sulfated 1 (human), hHLA-DQA2/Sulf:1

organism-modification


PR:000072766 HLA class II histocompatibility antigen, DQ alpha 2 chain hydroxylated 1 (human), hHLA-DQA2/Hy:1

organism-modification


PR:000076212 HLA class II histocompatibility antigen, DQ alpha 2 chain phosphorylated 1 (human), hHLA-DQA2/Phos:1

organism-modification


PR:000079435 HLA class II histocompatibility antigen, DQ alpha 2 chain methylated 2 (human), hHLA-DQA2/Me:2

organism-modification


PR:000085608 HLA class II histocompatibility antigen, DQ alpha 2 chain deaminated 1 (human), hHLA-DQA2/Deam:1

modification


PR:000018676 MHC class II histocompatibility antigen alpha chain DQA2, signal peptide removed form, MHCcIIalpha_DQA2/SigPep-

gene


PR:000002015 MHC class II histocompatibility antigen alpha chain DRA, MHCcIIalpha_DRA

organism-gene


PR:000050370 H-2 class II histocompatibility antigen, E alpha chain (mouse), mH2-Ea

organism-sequence


PR:P01904 H-2 class II histocompatibility antigen, E-D alpha chain (mouse), mH2-Ea/var:d

organism-sequence


PR:P04224 H-2 class II histocompatibility antigen, E-K alpha chain (mouse), mH2-Ea/var:k

organism-sequence


PR:P14439 H-2 class II histocompatibility antigen, E-U alpha chain (mouse), mH2-Ea/var:u

organism-gene


PR:E9M254 MHC class II antigen alpha (chicken), chick-HLA-DRA

organism-gene


PR:P01903 HLA class II histocompatibility antigen, DR alpha chain (human), hHLA-DRA

organism-modification


PR:000062250 HLA class II histocompatibility antigen, DR alpha chain, signal peptide removed form (human), hHLA-DRA/SigPep-

organism-modification


PR:000066282 HLA class II histocompatibility antigen, DR alpha chain deaminated 1 (human), hHLA-DRA/Deam:1

organism-modification


PR:000069543 HLA class II histocompatibility antigen, DR alpha chain deaminated 2 (human), hHLA-DRA/Deam:2

organism-modification


PR:000075864 HLA class II histocompatibility antigen, DR alpha chain cysteinylated 1 (human), hHLA-DRA/Cyst:1

organism-modification


PR:000077621 HLA class II histocompatibility antigen, DR alpha chain deaminated 3 (human), hHLA-DRA/Deam:3

organism-modification


PR:000078955 HLA class II histocompatibility antigen, DR alpha chain deaminated 4 (human), hHLA-DRA/Deam:4

organism-modification


PR:000082066 HLA class II histocompatibility antigen, DR alpha chain deaminated 5 (human), hHLA-DRA/Deam:5

organism-modification


PR:000082647 HLA class II histocompatibility antigen, DR alpha chain deaminated 6 (human), hHLA-DRA/Deam:6

organism-modification


PR:000085158 HLA class II histocompatibility antigen, DR alpha chain deaminated 7 (human), hHLA-DRA/Deam:7

modification


PR:000018678 MHC class II histocompatibility antigen alpha chain DRA, signal peptide removed form, MHCcIIalpha_DRA/SigPep-

gene


PR:000008612 MHC class II histocompatibility antigen, DO alpha chain, MHCcIIalpha_DO

organism-gene


PR:P06340 HLA class II histocompatibility antigen, DO alpha chain (human), hHLA-DOA

organism-modification


PR:000063284 HLA class II histocompatibility antigen, DO alpha chain, signal peptide removed form (human), hHLA-DOA/SigPep-

organism-modification


PR:000066515 HLA class II histocompatibility antigen, DO alpha chain deaminated 1 (human), hHLA-DOA/Deam:1

organism-modification


PR:000071975 HLA class II histocompatibility antigen, DO alpha chain cysteinylated 1 (human), hHLA-DOA/Cyst:1

organism-modification


PR:000072202 HLA class II histocompatibility antigen, DO alpha chain methylated 1 (human), hHLA-DOA/Me:1

organism-modification


PR:000076370 HLA class II histocompatibility antigen, DO alpha chain methylated 2 (human), hHLA-DOA/Me:2

organism-modification


PR:000080340 HLA class II histocompatibility antigen, DO alpha chain cysteinylated 2 (human), hHLA-DOA/Cyst:2

gene


PR:000030229 MHC class II histocompatibility antigen, DM alpha chain, MHCcIIalpha_DM

organism-gene


PR:P28067 HLA class II histocompatibility antigen, DM alpha chain (human), hHLA-DMA

organism-modification


PR:000061013 HLA class II histocompatibility antigen, DM alpha chain, signal peptide removed form (human), hHLA-DMA/SigPep-

organism-modification


PR:000065222 HLA class II histocompatibility antigen, DM alpha chain methylated 1 (human), hHLA-DMA/Me:1

organism-modification


PR:000065666 HLA class II histocompatibility antigen, DM alpha chain methylated 2 (human), hHLA-DMA/Me:2

organism-modification


PR:000066582 HLA class II histocompatibility antigen, DM alpha chain deaminated 1 (human), hHLA-DMA/Deam:1

organism-modification


PR:000070551 HLA class II histocompatibility antigen, DM alpha chain cysteinylated 1 (human), hHLA-DMA/Cyst:1

organism-modification


PR:000080577 HLA class II histocompatibility antigen, DM alpha chain deaminated 2 (human), hHLA-DMA/Deam:2

organism-gene


PR:000034771 H-2 class II histocompatibility antigen A alpha chain (mouse), mH2-Aa