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Protein Ontology report - PR domain zinc finger protein 1
PR:000001831 - http://purl.obolibrary.org/obo/PR_000001831
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001831   
  PRO namePR domain zinc finger protein 1 
  Synonyms
PRO-Short-label: EXACT:PRDM1
Gene-based: RELATED:BLIMP1
Other: EXACT:beta-interferon gene positive regulatory domain I-binding factor | BLIMP-1 | positive regulatory domain I-binding factor 1 | PR domain-containing protein 1 | PRDI-BF1 | PRDI-binding factor 1
  Definition"A protein that is a translation product of the human PRDM1 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF013212
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001831 PR domain zinc finger protein 1, PRDM1

organism-gene


PR:O75626 PR domain zinc finger protein 1 (human), hPRDM1

organism-sequence


PR:O75626-1 PR domain zinc finger protein 1 isoform 1 (human), hPRDM1/iso:1

organism-sequence


PR:O75626-2 PR domain zinc finger protein 1 isoform h2 (human), hPRDM1/iso:h2

organism-sequence


PR:O75626-3 PR domain zinc finger protein 1 isoform h3 (human), hPRDM1/iso:h3

organism-modification


PR:000066112 PR domain zinc finger protein 1 cysteinylated 1 (human), hPRDM1/Cyst:1

organism-gene


PR:Q60636 PR domain zinc finger protein 1 (mouse), mPRDM1

organism-sequence


PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse), mPRDM1/iso:1
Yes
organism-sequence


PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse), mPRDM1/iso:2
Yes
organism-sequence


PR:Q60636-3 PR domain zinc finger protein 1 isoform m3 (mouse), mPRDM1/iso:m3

organism-sequence


PR:Q60636-4 PR domain zinc finger protein 1 isoform m4 (mouse), mPRDM1/iso:m4

organism-sequence


PR:Q60636-5 PR domain zinc finger protein 1 isoform m5 (mouse), mPRDM1/iso:m5

sequence


PR:000026008 PR domain zinc finger protein 1 isoform 1, PRDM1/iso:1

organism-sequence


PR:D4A1S2 PR domain zinc finger protein 1 isoform 1 (rat), rPRDM1/iso:1

organism-sequence


PR:Q60636-1 PR domain zinc finger protein 1 isoform 1 (mouse), mPRDM1/iso:1
Yes
sequence


PR:000026009 PR domain zinc finger protein 1 isoform 2, PRDM1/iso:2

organism-sequence


PR:O75626-1 PR domain zinc finger protein 1 isoform 1 (human), hPRDM1/iso:1

organism-sequence


PR:Q60636-2 PR domain zinc finger protein 1 isoform 2 (mouse), mPRDM1/iso:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q60636-1 mPRDM1/iso:1

"A PR domain zinc finger protein 1 isoform 1 that is encoded in the genome of mouse." [PMID:8168136, PRO:HJD]		 acts_upstream_of_or_withinGO:0030889 negative regulation of B cell proliferation MGI:3826899; PMID:18845144
GO:0045579 positive regulation of B cell differentiation MGI:3826899; PMID:18845144
enablesGO:0005515 protein binding with PR:Q60636-1 MGI:3826899; PMID:18845144
GO:0005515 protein binding with PR:Q60636-2 MGI:3826899; PMID:18845144
GO:0042826 histone deacetylase binding MGI:3826899; PMID:18845144
GO:0043565 sequence-specific DNA binding MGI:3826899; PMID:18845144
located_inGO:0005634 nucleus MGI:3826899; PMID:18845144
PR:Q60636-2 mPRDM1/iso:2
Blimp-1delta7 (mouse)
"A PR domain zinc finger protein 1 isoform 2 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]		 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II MGI:3826899; PMID:18845144
GO:0030889 negative regulation of B cell proliferation MGI:3826899; PMID:18845144
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway MGI:3826899; PMID:18845144
NOT GO:0045579 positive regulation of B cell differentiation MGI:3826899; PMID:18845144
enablesGO:0005515 protein binding with PR:Q60636-1 MGI:3826899; PMID:18845144
GO:0005515 protein binding with PR:Q60636-2 MGI:3826899; PMID:18845144
GO:0042826 histone deacetylase binding MGI:3826899; PMID:18845144
located_inGO:0005737 cytoplasm MGI:3826899; PMID:18845144