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Protein Ontology report - fractalkine
PR:000001855 - http://purl.obolibrary.org/obo/PR_000001855
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001855   
  PRO namefractalkine 
  Synonyms
PRO-Short-label: EXACT:CX3CL1
Gene-based: RELATED:A-152E5.2 | Cx3c | FKN | NTT | SCYD1
Other: EXACT:C-X3-C motif chemokine 1 | CX3C membrane-anchored chemokine | neurotactin | small-inducible cytokine D1
  Definition"A protein that is a translation product of the human CX3CL1 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification3                                                  Organism-Modification 12                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038029
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001855 fractalkine, CX3CL1

organism-gene


PR:O35188 fractalkine (mouse), mCX3CL1

organism-sequence


PR:Q9Z0D9-1 CX3C chemokine receptor 1 isoform 1 (mouse), mCX3CR1/iso:1
Yes
organism-gene


PR:O55145 fractalkine (rat), rCX3CL1

organism-gene


PR:P78423 fractalkine (human), hCX3CL1

organism-modification


PR:000047104 fractalkine, signal peptide removed form (human), hCX3CL1/SigPep-

organism-modification


PR:000056679 fractalkine O-glycosylated 1 (human), hCX3CL1/OGlyco:1

organism-modification


PR:000056680 fractalkine O-glycosylated 2 (human), hCX3CL1/OGlyco:2

organism-modification


PR:000056681 fractalkine O-glycosylated 3 (human), hCX3CL1/OGlyco:3

organism-modification


PR:000056682 fractalkine O-glycosylated 4 (human), hCX3CL1/OGlyco:4

organism-modification


PR:000056683 fractalkine O-glycosylated 5 (human), hCX3CL1/OGlyco:5

organism-modification


PR:000056684 fractalkine O-glycosylated 6 (human), hCX3CL1/OGlyco:6

organism-modification


PR:000056685 fractalkine O-glycosylated 7 (human), hCX3CL1/OGlyco:7

organism-modification


PR:000056686 fractalkine O-glycosylated 8 (human), hCX3CL1/OGlyco:8

organism-modification


PR:000056687 fractalkine O-glycosylated 9 (human), hCX3CL1/OGlyco:9

organism-modification


PR:000056688 fractalkine O-glycosylated 10 (human), hCX3CL1/OGlyco:10

organism-modification


PR:000069531 fractalkine cysteinylated 1 (human), hCX3CL1/Cyst:1

sequence


PR:000002982 fractalkine isoform 1, CX3CL1/iso:1

organism-sequence


PR:Q9Z0D9-1 CX3C chemokine receptor 1 isoform 1 (mouse), mCX3CR1/iso:1
Yes
modification


PR:000021941 fractalkine isoform 1, signal peptide removed form, CX3CL1/iso:1/SigPep-

modification


PR:000018549 fractalkine, signal peptide removed form, CX3CL1/SigPep-

modification


PR:000021941 fractalkine isoform 1, signal peptide removed form, CX3CL1/iso:1/SigPep-

organism-modification


PR:000047104 fractalkine, signal peptide removed form (human), hCX3CL1/SigPep-

modification


PR:000018550 fractalkine proteolytic cleavage product, CX3CL1/ClvPrd

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9Z0D9-1
mCX3CR1/iso:1
 acts_upstream_of_or_withinGO:0002282 microglial cell activation involved in immune response MGI:3639805; PMID:16732273
GO:0019221 cytokine-mediated signaling pathway MGI:3833195; PMID:18971423
GO:0021795 cerebral cortex cell migration MGI:3639805; PMID:16732273
GO:0048246 macrophage chemotaxis MGI:3777228; PMID:18322241
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand MGI:3833195; PMID:18971423