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Protein Ontology report - receptor-type tyrosine-protein kinase Tie
PR:000001923 - http://purl.obolibrary.org/obo/PR_000001923
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001923   
  PRO namereceptor-type tyrosine-protein kinase Tie 
  Definition"A protein with core architecture consisting of an extracellular region containing an Ig-like domain (Pfam:PF00047 or Pfam:PF10430), followed by 3 EGF-like domains (Pfam:PF07947 or Pfam:PF00053), another Ig-like domain, and 3 Fibronectin type III domains (Pfam:PF00041), and a cytoplasmic region containing the Protein tyrosine kinase domain (Pfam:PF07714)." [PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 9                                        
         Modification3                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF000630
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001923 receptor-type tyrosine-protein kinase Tie, CD164

gene


PR:000002032 angiopoietin-1 receptor, TEK

organism-gene


PR:O73791 angiopoietin-1 receptor (zebrafish), z-TEK

organism-gene


PR:Q02763 angiopoietin-1 receptor (human), hTEK

organism-sequence


PR:000002131 angiopoietin-1 receptor sequence variant R849W (human), hTEK/var:R849W
Yes
organism-sequence


PR:000002132 angiopoietin-1 receptor sequence variant Y897S (human), hTEK/var:Y897S
Yes
organism-sequence


PR:Q02763-1 angiopoietin-1 receptor isoform 1 (human), hTEK/iso:1

organism-sequence


PR:Q02763-2 angiopoietin-1 receptor isoform h2 (human), hTEK/iso:h2

organism-sequence


PR:Q02763-3 angiopoietin-1 receptor isoform h3 (human), hTEK/iso:h3

organism-modification


PR:000049418 angiopoietin-1 receptor, signal peptide removed form (human), hTEK/SigPep-

organism-modification


PR:000049419 angiopoietin-1 receptor, signal peptide removed phosphorylated 1 (human), hTEK/SigPep-/Phos:1

organism-modification


PR:000056851 angiopoietin-1 receptor N-glycosylated 1 (human), hTEK/NGlyco:1

organism-modification


PR:000081311 angiopoietin-1 receptor deaminated 1 (human), hTEK/Deam:1

organism-gene


PR:Q02858 angiopoietin-1 receptor (mouse), mTEK

organism-sequence


PR:Q02858-1 angiopoietin-1 receptor isoform 1 (mouse), mTEK/iso:1

sequence


PR:000002130 angiopoietin-1 receptor isoform 1, TEK/iso:1

organism-sequence


PR:Q02763-1 angiopoietin-1 receptor isoform 1 (human), hTEK/iso:1

organism-sequence


PR:Q02858-1 angiopoietin-1 receptor isoform 1 (mouse), mTEK/iso:1

modification


PR:000026692 angiopoietin-1 receptor isoform 1, signal peptide removed form, TEK/iso:1/SigPep-

modification


PR:000018700 angiopoietin-1 receptor, signal peptide removed form, TEK/SigPep-

modification


PR:000026692 angiopoietin-1 receptor isoform 1, signal peptide removed form, TEK/iso:1/SigPep-

organism-modification


PR:000049418 angiopoietin-1 receptor, signal peptide removed form (human), hTEK/SigPep-

organism-modification


PR:000049419 angiopoietin-1 receptor, signal peptide removed phosphorylated 1 (human), hTEK/SigPep-/Phos:1

gene


PR:000016330 tyrosine-protein kinase receptor Tie-1, TIE1

organism-gene


PR:P35590 tyrosine-protein kinase receptor Tie-1 (human), hTIE1

organism-sequence


PR:P35590-1 tyrosine-protein kinase receptor Tie-1 isoform h1 (human), hTIE1/iso:h1

organism-sequence


PR:P35590-2 tyrosine-protein kinase receptor Tie-1 isoform h2 (human), hTIE1/iso:h2

organism-sequence


PR:P35590-3 tyrosine-protein kinase receptor Tie-1 isoform h3 (human), hTIE1/iso:h3

organism-gene


PR:Q06806 tyrosine-protein kinase receptor Tie-1 (mouse), mTIE1

modification


PR:000021667 tyrosine-protein kinase receptor Tie-1, signal peptide removed form, TIE1/SigPep-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000002131 hTEK/var:R849W
UniProtKB:Q02763, Arg-849, CHEBI:29954 | UniProtKB:Q02763-1, Arg-849, CHEBI:29954 | angiopoietin-1 receptor sequence variant 1 (human)
"An angiopoietin-1 receptor (human) that has a Trp residue at the position equivalent to Arg-849 of the amino acid sequence represented by UniProtKB:Q02763-1. Example: UniProtKB:Q02763-1, Arg-849, CHEBI:29954." [PMID:10369874, PMID:8980225, PMID:99199243, PRO:CNA, PRO:DAN]		 associated_with_disease_progressionDO:0050792 multiple cutaneous and mucosal venous malformations PMID:10369874; PMID:8980225
enablesGO:0005515 protein binding with PR:P27986-1 PMID:10369874
PR:000002132 hTEK/var:Y897S
UniProtKB:Q02763, Tyr-897, CHEBI:29999 | UniProtKB:Q02763-1, Tyr-897, CHEBI:29999 | angiopoietin-1 receptor sequence variant 2 (human)
"An angiopoietin-1 receptor (human) that has a Ser residue at the position equivalent to Tyr-897 of the amino acid sequence represented by UniProtKB:Q02763-1. Example: UniProtKB:Q02763-1, Tyr-897, CHEBI:29999." [PMID:10369874, PRO:CNA, PRO:DAN]		 associated_with_disease_progressionDO:0050792 multiple cutaneous and mucosal venous malformations PMID:10369874
enablesGO:0005515 protein binding with PR:P27986-1 PMID:10369874