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Protein Ontology report - beta-type platelet-derived growth factor receptor
PR:000002035 - http://purl.obolibrary.org/obo/PR_000002035
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002035   
  PRO namebeta-type platelet-derived growth factor receptor 
  Synonyms
PRO-Short-label: EXACT:PDGFRB
Gene-based: RELATED:PDGFR1
Other: EXACT:beta platelet-derived growth factor receptor | CD140 antigen-like family member B | CD140b | PDGF-R-beta | PDGFR-1 | PDGFR-beta | platelet-derived growth factor receptor 1
RELATED:Pdgfr
  Definition"A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human PDGFRB gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001810
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification4                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500948;IUPHARobj:1804
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002035 beta-type platelet-derived growth factor receptor, PDGFRB

organism-gene


PR:P05622 platelet-derived growth factor receptor beta (mouse), mPDGFRB

organism-sequence


PR:P05622-1 platelet-derived growth factor receptor beta isoform 1 (mouse), mPDGFRB/iso:1

organism-sequence


PR:P05622-2 platelet-derived growth factor receptor beta isoform m2 (mouse), mPDGFRB/iso:m2

organism-gene


PR:P09619 platelet-derived growth factor receptor beta (human), hPDGFRB

organism-sequence


PR:P09619-1 platelet-derived growth factor receptor beta isoform 1 (human), hPDGFRB/iso:1

organism-sequence


PR:P09619-2 platelet-derived growth factor receptor beta isoform h2 (human), hPDGFRB/iso:h2

organism-modification


PR:000048725 platelet-derived growth factor receptor beta, signal peptide removed form (human), hPDGFRB/SigPep-

organism-modification


PR:000048726 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 1 (human), hPDGFRB/SigPep-/Phos:1

organism-modification


PR:000049846 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human), hPDGFRB/SigPep-/Phos:2
Yes
organism-modification


PR:000049847 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human), hPDGFRB/SigPep-/Phos:3
Yes
organism-modification


PR:000049848 platelet-derived growth factor receptor beta, signal peptide removed unphosphorylated 2 (human), hPDGFRB/SigPep-/UnPhos:2
Yes
organism-modification


PR:000064602 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 4 (human), hPDGFRB/SigPep-/Phos:4

organism-gene


PR:Q05030 platelet-derived growth factor receptor beta (rat), rPDGFRB

sequence


PR:000002136 beta-type platelet-derived growth factor receptor isoform 1, PDGFRB/iso:1

organism-sequence


PR:P05622-1 platelet-derived growth factor receptor beta isoform 1 (mouse), mPDGFRB/iso:1

modification


PR:000026683 beta-type platelet-derived growth factor receptor isoform 1, signal peptide removed form, PDGFRB/iso:1/SigPep-

sequence


PR:000002137 beta-type platelet-derived growth factor receptor isoform 2, PDGFRB/iso:2

organism-sequence


PR:P09619-1 platelet-derived growth factor receptor beta isoform 1 (human), hPDGFRB/iso:1

modification


PR:000002143 beta-type platelet-derived growth factor receptor isoform 2, signal peptide removed form, PDGFRB/iso:2/SigPep-

modification


PR:000018702 beta-type platelet-derived growth factor receptor, signal peptide removed form, PDGFRB/SigPep-

modification


PR:000002143 beta-type platelet-derived growth factor receptor isoform 2, signal peptide removed form, PDGFRB/iso:2/SigPep-

modification


PR:000026683 beta-type platelet-derived growth factor receptor isoform 1, signal peptide removed form, PDGFRB/iso:1/SigPep-

organism-modification


PR:000048725 platelet-derived growth factor receptor beta, signal peptide removed form (human), hPDGFRB/SigPep-

organism-modification


PR:000048726 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 1 (human), hPDGFRB/SigPep-/Phos:1

organism-modification


PR:000049846 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human), hPDGFRB/SigPep-/Phos:2
Yes
organism-modification


PR:000049847 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human), hPDGFRB/SigPep-/Phos:3
Yes
organism-modification


PR:000049848 platelet-derived growth factor receptor beta, signal peptide removed unphosphorylated 2 (human), hPDGFRB/SigPep-/UnPhos:2
Yes
modification


PR:000025415 beta-type platelet-derived growth factor receptor proteolytic cleavage product, PDGFRB/ClvPrd

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000049846
hPDGFRB/SigPep-/Phos:2
UniProtKB:P09619, 33-1106, Tyr-857, MOD:00048 | UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048		 acts_upstream_of_or_withinincreased GO:0018108 peptidyl-tyrosine phosphorylation relative to PR:000049848 hPDGFRB/SigPep-/UnPhos:2 PMID:1653029; PMID:9642269
enablesGO:0004713 protein tyrosine kinase activity PMID:15994317; PMID:9642269
increased GO:0005515 protein binding relative to PR:000049848 hPDGFRB/SigPep-/UnPhos:2 PMID:1653029
PR:000049847
hPDGFRB/SigPep-/Phos:3
UniProtKB:P09619, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046 | UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046		 acts_upstream_of_or_withindecreased GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15271984
enablesdecreased GO:0004713 protein tyrosine kinase activity relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15271984
decreased GO:0005515 protein binding relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15271984
PR:000049848
hPDGFRB/SigPep-/UnPhos:2
UniProtKB:P09619, 33-1106, Tyr-857, PR:000026291 | UniProtKB:P09619-1, 33-1106, Tyr-857, PR:000026291		 acts_upstream_of_or_withinGO:0038083 peptidyl-tyrosine autophosphorylation PMID:9642269