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Protein Ontology report - caspase-3-like protease
PR:000002196 - http://purl.obolibrary.org/obo/PR_000002196
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000002196   
  PRO namecaspase-3-like protease 
  Definition"A protein that is a translation product of a gene family that includes CASP3, CASP6, and CASP7 genes. The core architecture consists of a Caspase domain (Pfam:PF00656). Encoded as zymogens, the activated proteins are cysteine proteases typically involved in apoptosis." [PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family0                                                  Organism-Family 0                                        
         Gene0                                                  Organism-Gene 0                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF015839
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000002196 caspase-3-like protease, APAF1

gene


PR:000002312 caspase-3, CASP3

organism-gene


PR:P42574 caspase-3 (human), hCASP3

organism-sequence


PR:P42574-1 caspase-3 isoform 1 (human), hCASP3/iso:1

organism-modification


PR:000026876 caspase-3 isoform 1 cleaved 1 (human), hCASP3/iso:1/Clv:1

Yes
organism-modification


PR:000026877 caspase-3 isoform 1 cleaved 2 (human), hCASP3/iso:1/Clv:2

Yes
organism-modification


PR:000082245 caspase-3 cysteinylated 1 (human), hCASP3/Cyst:1

organism-gene


PR:P55213 caspase-3 (rat), rCASP3

organism-gene


PR:P70677 caspase-3 (mouse), mCASP3

organism-sequence


PR:P70677-1 caspase-3 isoform 1 (mouse), mCASP3/iso:1

sequence


PR:000002402 caspase-3 isoform 1, CASP3/iso:1

organism-sequence


PR:P42574-1 caspase-3 isoform 1 (human), hCASP3/iso:1

organism-modification


PR:000026876 caspase-3 isoform 1 cleaved 1 (human), hCASP3/iso:1/Clv:1

Yes
organism-modification


PR:000026877 caspase-3 isoform 1 cleaved 2 (human), hCASP3/iso:1/Clv:2

Yes
organism-sequence


PR:P70677-1 caspase-3 isoform 1 (mouse), mCASP3/iso:1

modification


PR:000002454 caspase-3 isoform 1 cleaved 1, CASP3/iso:1/Clv:1

Yes
organism-modification


PR:000026876 caspase-3 isoform 1 cleaved 1 (human), hCASP3/iso:1/Clv:1

Yes
modification


PR:000002455 caspase-3 isoform 1 cleaved 2, CASP3/iso:1/Clv:2

Yes
organism-modification


PR:000026877 caspase-3 isoform 1 cleaved 2 (human), hCASP3/iso:1/Clv:2

Yes
modification


PR:000018762 caspase-3 proteolytic cleavage product, CASP3/ClvPrd

modification


PR:000002454 caspase-3 isoform 1 cleaved 1, CASP3/iso:1/Clv:1

Yes
organism-modification


PR:000026876 caspase-3 isoform 1 cleaved 1 (human), hCASP3/iso:1/Clv:1

Yes
modification


PR:000002455 caspase-3 isoform 1 cleaved 2, CASP3/iso:1/Clv:2

Yes
organism-modification


PR:000026877 caspase-3 isoform 1 cleaved 2 (human), hCASP3/iso:1/Clv:2

Yes
gene


PR:000002315 caspase-6, CASP6

organism-gene


PR:A0A1D5PPP7 caspase-6 (chicken), chick-CASP6

organism-gene


PR:O08738 caspase-6 (mouse), mCASP6

organism-sequence


PR:O08738-1 caspase-6 isoform 1 (mouse), mCASP6/iso:1

organism-gene


PR:O35397 caspase-6 (rat), rCASP6

organism-gene


PR:P55212 caspase-6 (human), hCASP6

organism-sequence


PR:P55212-1 caspase-6 isoform Alpha (human), hCASP6/iso:Alpha

organism-modification


PR:000050093 caspase-6 subunit p18 (human), hCASP6/p18

organism-modification


PR:000050094 caspase-6 subunit p11 (human), hCASP6/p11

organism-sequence


PR:P55212-2 caspase-6 isoform Beta (human), hCASP6/iso:Beta

organism-modification


PR:000045840 caspase-6 phosphorylated 1 (human), hCASP6/Phos:1

organism-modification


PR:000067313 caspase-6 cysteinylated 1 (human), hCASP6/Cyst:1

sequence


PR:000002406 caspase-6 isoform 1, CASP6/iso:1

organism-sequence


PR:P55212-1 caspase-6 isoform Alpha (human), hCASP6/iso:Alpha

organism-modification


PR:000050093 caspase-6 subunit p18 (human), hCASP6/p18

organism-modification


PR:000050094 caspase-6 subunit p11 (human), hCASP6/p11

modification


PR:000002456 caspase-6 subunit p11, CASP6/p11

organism-modification


PR:000050094 caspase-6 subunit p11 (human), hCASP6/p11

modification


PR:000002457 caspase-6 subunit p18, CASP6/p18

organism-modification


PR:000050093 caspase-6 subunit p18 (human), hCASP6/p18

sequence


PR:000002407 caspase-6 isoform 2, CASP6/iso:2

organism-sequence


PR:O08738-1 caspase-6 isoform 1 (mouse), mCASP6/iso:1

sequence


PR:000002408 caspase-6 isoform 3, CASP6/iso:3

organism-sequence


PR:P55212-2 caspase-6 isoform Beta (human), hCASP6/iso:Beta

modification


PR:000018765 caspase-6 proteolytic cleavage product, CASP6/ClvPrd

modification


PR:000002456 caspase-6 subunit p11, CASP6/p11

organism-modification


PR:000050094 caspase-6 subunit p11 (human), hCASP6/p11

modification


PR:000002457 caspase-6 subunit p18, CASP6/p18

organism-modification


PR:000050093 caspase-6 subunit p18 (human), hCASP6/p18

gene


PR:000002316 caspase-7, CASP7





PR:000002409 caspase-7 isoform 1,





PR:P97864-1 caspase-7 isoform 1 (mouse),





PR:000002458 caspase-7 subunit p11,

organism-modification


PR:000050106 caspase-7 subunit p11 (human), hCASP7/p11





PR:000002459 caspase-7 subunit p20,

organism-modification


PR:000050105 caspase-7 subunit p20 (human), hCASP7/p20

organism-sequence


PR:P55210-1 caspase-7 isoform Alpha (human), hCASP7/iso:Alpha

organism-modification


PR:000050105 caspase-7 subunit p20 (human), hCASP7/p20

organism-modification


PR:000050106 caspase-7 subunit p11 (human), hCASP7/p11





PR:000002410 caspase-7 isoform 2,





PR:P55210-2 caspase-7 isoform Beta (human),





PR:000002411 caspase-7 isoform 3,





PR:P55210-3 caspase-7 isoform Alpha' (human),





PR:000018766 caspase-7, initiator methionine removed form,





PR:000018767 caspase-7 proteolytic cleavage product,





PR:000002458 caspase-7 subunit p11,

organism-modification


PR:000050106 caspase-7 subunit p11 (human), hCASP7/p11





PR:000002459 caspase-7 subunit p20,

organism-modification


PR:000050105 caspase-7 subunit p20 (human), hCASP7/p20

organism-gene


PR:F1NV61 caspase-7 (chicken), chick-CASP7

organism-gene


PR:O01382 caspase (fruit fly), fly-CASP7

organism-gene


PR:P55210 caspase-7 (human), hCASP7

organism-sequence


PR:P55210-1 caspase-7 isoform Alpha (human), hCASP7/iso:Alpha

organism-modification


PR:000050105 caspase-7 subunit p20 (human), hCASP7/p20

organism-modification


PR:000050106 caspase-7 subunit p11 (human), hCASP7/p11





PR:P55210-2 caspase-7 isoform Beta (human),





PR:P55210-3 caspase-7 isoform Alpha' (human),





PR:P55210-4 caspase-7 isoform h4 (human),





PR:P97864 caspase-7 (mouse),





PR:P97864-1 caspase-7 isoform 1 (mouse),

gene


PR:000005054 caspase-14, CASP14

organism-gene


PR:O89094 caspase-14 (mouse), mCASP14

organism-sequence


PR:O89094-1 caspase-14 isoform m1 (mouse), mCASP14/iso:m1

organism-sequence


PR:O89094-2 caspase-14 isoform m2 (mouse), mCASP14/iso:m2

organism-gene


PR:P31944 caspase-14 (human), hCASP14

modification


PR:000019242 caspase-14 proteolytic cleavage product, CASP14/ClvPrd

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APAF1 forms found in complexes   

APAF1 Component
 Complexes
PR:000002454 CASP3/iso:1/Clv:1 PR:000026878 caspase-3 complex
PR:000002455 CASP3/iso:1/Clv:2 PR:000026878 caspase-3 complex
PR:000026876 hCASP3/iso:1/Clv:1 PR:000026879 caspase-3 complex (human)
PR:000026877 hCASP3/iso:1/Clv:2 PR:000026879 caspase-3 complex (human)