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Protein Ontology report - Bcl-2-like protein 1
PR:000002308 - http://purl.obolibrary.org/obo/PR_000002308
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002308   
  PRO nameBcl-2-like protein 1 
  Synonyms
PRO-Short-label: EXACT:BCL2L1
Gene-based: RELATED:BCL2L | BCLX
Other: EXACT:apoptosis regulator Bcl-X | Bcl2-L-1
  Definition"A Bcl-2-like apoptosis inhibitor that is a translation product of the human BCL2L1 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000002186
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence5                                                  Organism-Sequence 12                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2845
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002308 Bcl-2-like protein 1, BCL2L1

organism-gene


PR:P53563 Bcl-2-like protein 1 (rat), rBCL2L1

organism-sequence


PR:P53563-1 Bcl-2-like protein 1 isoform Bcl-X(L) (rat), rBcl2l1/iso:Bcl-X(L)

organism-sequence


PR:P53563-2 Bcl-2-like protein 1 isoform Bcl-X(S) (rat), rBCL2L1/iso:Bcl-X(S)

organism-sequence


PR:P53563-3 Bcl-2-like protein 1 isoform Bcl-X(beta) (rat), rBCL2L1/iso:Bcl-X(beta)

organism-gene


PR:Q07816 Bcl-2-like protein 1 (chicken), chick-BCL2L1

organism-sequence


PR:Q07816-1 Bcl-2-like protein 1 isoform Long (chicken), chick-BCL2L1/iso:Long

organism-sequence


PR:Q07816-2 Bcl-2-like protein 1 isoform Short (chicken), chick-BCL2L1/iso:Short

organism-gene


PR:Q07817 Bcl-2-like protein 1 (human), hBCL2L1

organism-sequence


PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human), hBCL2L1/iso:1
Yes
organism-sequence


PR:Q07817-2 Bcl-2-like protein 1 isoform Bcl-X(S) (human), hBCL2L1/iso:Bcl-X(S)

organism-sequence


PR:Q07817-3 Bcl-2-like protein 1 isoform Bcl-X(beta) (human), hBCL2L1/iso:Bcl-X(beta)

organism-modification


PR:000045887 Bcl-2-like protein 1 phosphorylated 1 (human), hBCL2L1/Phos:1

organism-gene


PR:Q64373 Bcl-2-like protein 1 (mouse), mBCL2L1

organism-sequence


PR:Q64373-1 Bcl-2-like protein 1 isoform Bcl-X(L) (mouse), mBCL2L1/iso:Bcl-X(L)
Yes
organism-sequence


PR:Q64373-2 Bcl-2-like protein 1 isoform Bcl-X(S) (mouse), mBCL2L1/iso:Bcl-X(S)
Yes
organism-sequence


PR:Q64373-3 Bcl-2-like protein 1 isoform Bcl-X(beta) (mouse), mBCL2L1/iso:Bcl-X(beta)

organism-sequence


PR:Q64373-4 Bcl-2-like protein 1 isoform Bcl-X(delta-TM) (mouse), mBCL2L1/iso:Bcl-X(delta-TM)

sequence


PR:000002385 Bcl-2-like protein 1 isoform 1, BCL2L1/iso:1

organism-sequence


PR:Q07817-1 Bcl-2-like protein 1 isoform 1 (human), hBCL2L1/iso:1
Yes
organism-sequence


PR:Q64373-1 Bcl-2-like protein 1 isoform Bcl-X(L) (mouse), mBCL2L1/iso:Bcl-X(L)
Yes
sequence


PR:000002386 Bcl-2-like protein 1 isoform 2, BCL2L1/iso:2

organism-sequence


PR:Q07817-2 Bcl-2-like protein 1 isoform Bcl-X(S) (human), hBCL2L1/iso:Bcl-X(S)

organism-sequence


PR:Q64373-2 Bcl-2-like protein 1 isoform Bcl-X(S) (mouse), mBCL2L1/iso:Bcl-X(S)
Yes
sequence


PR:000002387 Bcl-2-like protein 1 isoform 3, BCL2L1/iso:3

organism-sequence


PR:Q07817-3 Bcl-2-like protein 1 isoform Bcl-X(beta) (human), hBCL2L1/iso:Bcl-X(beta)

sequence


PR:000002388 Bcl-2-like protein 1 isoform 4, BCL2L1/iso:4

organism-sequence


PR:Q64373-3 Bcl-2-like protein 1 isoform Bcl-X(beta) (mouse), mBCL2L1/iso:Bcl-X(beta)

sequence


PR:000002389 Bcl-2-like protein 1 isoform 5, BCL2L1/iso:5

organism-sequence


PR:Q64373-4 Bcl-2-like protein 1 isoform Bcl-X(delta-TM) (mouse), mBCL2L1/iso:Bcl-X(delta-TM)

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q07817-1
hBCL2L1/iso:1
 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:10949026
GO:0043066 negative regulation of apoptotic process PMID:8596636
enablesNOT GO:0005515 protein binding with PR:000028379 hBID/iso:1/Clv:1 PMID:10949026
NOT GO:0005515 protein binding with PR:O54918 Bcl2-interacting mediator of cell death (mouse) PMID:10949026
NOT GO:0005515 protein binding with PR:Q07812 BAX PMID:10949026
NOT GO:0005515 protein binding with PR:Q16611 apoptosis regulator BAK (human) PMID:10949026
NOT GO:0005515 protein binding with PR:Q61337 Bad PMID:10949026
NOT GO:0005515 protein binding with PR:Q92934-1 PMID:10949026
NOT GO:0005515 protein binding with PR:000026167 mBAD/iso:1/Phos:1 PMID:10949026
NOT GO:0005515 protein binding with PR:000026133 mBAD/iso:1/Phos:2 PMID:10949026
PR:Q64373-1
mBCL2L1/iso:Bcl-X(L)
Bcl-2-like protein 1 isoform Bcl-xL (mouse)		 acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process MGI:81233; PMID:8798158
GO:0043066 negative regulation of apoptotic process MGI:81233; PMID:8798158
associated_with_disease_progressionDO:162 cancer PMID:16403219
enablesGO:0005515 protein binding with PR:O08734 apoptosis regulator BAK (mouse) MGI:3804133; PMID:16705087
GO:0046982 protein heterodimerization activity MGI:82784; PMID:8798452
PR:Q64373-2
mBCL2L1/iso:Bcl-X(S)
Bcl-2-like protein 1 isoform Bcl-xS (mouse)		 acts_upstream_of_or_withinGO:0043065 positive regulation of apoptotic process MGI:81233; PMID:8798158