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Protein Ontology report - caspase-8
PR:000002317 - http://purl.obolibrary.org/obo/PR_000002317
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000002317   
  PRO namecaspase-8 
  Synonyms
PRO-Short-label: EXACT:CASP8
Gene-based: RELATED:MCH5
Other: EXACT:apoptotic cysteine protease | apoptotic protease Mch-5 | CAP4 | CASP-8 | FADD-homologous ICE/ced-3-like protease | FADD-like ICE | FLICE | ICE-like apoptotic protease 5 | MACH | MORT1-associated ced-3 homolog
  Definition"A caspase-8-like protease that is a translation product of the human CASP8 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000002197
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence9                                                  Organism-Sequence 10                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500656;IUPHARobj:1624
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002317 caspase-8, CASP8

organism-gene


PR:O89110 caspase-8 (mouse), mCASP8

organism-sequence


PR:O89110-1 caspase-8 isoform 1 (mouse), mCASP8/iso:1

organism-gene


PR:Q14790 caspase-8 (human), hCASP8

Yes
organism-sequence


PR:Q14790-1 caspase-8 isoform 1 (human), hCASP8/iso:1

organism-modification


PR:000036063 caspase-8 isoform 1 cleaved 1 (human), hCASP8/iso:1/Clv:1

Yes
organism-modification


PR:000036065 caspase-8 isoform 1 cleaved 2 (human), hCASP8/iso:1/Clv:2

Yes
organism-sequence


PR:Q14790-2 caspase-8 isoform 2 (human), hCASP8/iso:2

organism-sequence


PR:Q14790-3 caspase-8 isoform 3 (human), hCASP8/iso:3

organism-sequence


PR:Q14790-4 caspase-8 isoform 4 (human), hCASP8/iso:4

organism-sequence


PR:Q14790-5 caspase-8 isoform 5 (human), hCASP8/iso:5

organism-sequence


PR:Q14790-6 caspase-8 isoform 6 (human), hCASP8/iso:6

organism-sequence


PR:Q14790-7 caspase-8 isoform 7 (human), hCASP8/iso:7

organism-sequence


PR:Q14790-8 caspase-8 isoform 8 (human), hCASP8/iso:8

organism-sequence


PR:Q14790-9 caspase-8 isoform 9 (human), hCASP8/iso:9

organism-modification


PR:000045931 caspase-8 phosphorylated 1 (human), hCASP8/Phos:1

organism-gene


PR:Q9JHX4 caspase-8 (rat), rCASP8

sequence


PR:000002412 caspase-8 isoform 1, CASP8/iso:1

organism-sequence


PR:O89110-1 caspase-8 isoform 1 (mouse), mCASP8/iso:1

organism-sequence


PR:Q14790-1 caspase-8 isoform 1 (human), hCASP8/iso:1

organism-modification


PR:000036063 caspase-8 isoform 1 cleaved 1 (human), hCASP8/iso:1/Clv:1

Yes
organism-modification


PR:000036065 caspase-8 isoform 1 cleaved 2 (human), hCASP8/iso:1/Clv:2

Yes
modification


PR:000036062 caspase-8 isoform 1 cleaved 1, CASP8/iso:1/Clv:1

organism-modification


PR:000036063 caspase-8 isoform 1 cleaved 1 (human), hCASP8/iso:1/Clv:1

Yes
modification


PR:000036064 caspase-8 isoform 1 cleaved 2, CASP8/iso:1/Clv:2

organism-modification


PR:000036065 caspase-8 isoform 1 cleaved 2 (human), hCASP8/iso:1/Clv:2

Yes
sequence


PR:000002413 caspase-8 isoform 2, CASP8/iso:2

organism-sequence


PR:Q14790-2 caspase-8 isoform 2 (human), hCASP8/iso:2

sequence


PR:000002414 caspase-8 isoform 3, CASP8/iso:3

organism-sequence


PR:Q14790-3 caspase-8 isoform 3 (human), hCASP8/iso:3

sequence


PR:000002415 caspase-8 isoform 4, CASP8/iso:4

organism-sequence


PR:Q14790-4 caspase-8 isoform 4 (human), hCASP8/iso:4

sequence


PR:000002416 caspase-8 isoform 5, CASP8/iso:5

organism-sequence


PR:Q14790-5 caspase-8 isoform 5 (human), hCASP8/iso:5

sequence


PR:000002417 caspase-8 isoform 6, CASP8/iso:6

organism-sequence


PR:Q14790-6 caspase-8 isoform 6 (human), hCASP8/iso:6

sequence


PR:000002418 caspase-8 isoform 7, CASP8/iso:7

organism-sequence


PR:Q14790-7 caspase-8 isoform 7 (human), hCASP8/iso:7

sequence


PR:000002419 caspase-8 isoform 8, CASP8/iso:8

organism-sequence


PR:Q14790-8 caspase-8 isoform 8 (human), hCASP8/iso:8

sequence


PR:000002420 caspase-8 isoform 9, CASP8/iso:9

organism-sequence


PR:Q14790-9 caspase-8 isoform 9 (human), hCASP8/iso:9

modification


PR:000018768 caspase-8 proteolytic cleavage product, CASP8/ClvPrd

modification


PR:000036062 caspase-8 isoform 1 cleaved 1, CASP8/iso:1/Clv:1

organism-modification


PR:000036063 caspase-8 isoform 1 cleaved 1 (human), hCASP8/iso:1/Clv:1

Yes
modification


PR:000036064 caspase-8 isoform 1 cleaved 2, CASP8/iso:1/Clv:2

organism-modification


PR:000036065 caspase-8 isoform 1 cleaved 2 (human), hCASP8/iso:1/Clv:2

Yes
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CASP8 forms found in complexes   

CASP8 Component
 Complexes
PR:000036063 hCASP8/iso:1/Clv:1 PR:000036068
PR:000036065 hCASP8/iso:1/Clv:2 PR:000036068
PR:Q14790 hCASP8 PR:000028435^P000036060^P000037368