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RACE-PRO
PRO tracker
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Documentation
Protein Ontology report - Bcl-2-like protein 1 isoform 1
PR:000002385 -
http://purl.obolibrary.org/obo/PR_000002385
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000002385
PRO name
Bcl-2-like protein 1 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
BCL2L1/iso:1
Other
:
EXACT:
Bcl-2-like protein 1 isoform Bcl-X(L)
RELATED:
apoptosis regulator Bcl-X isoform 1
Definition
"A Bcl-2-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q64373-1
or a 1:1 ortholog thereof." [PRO:JAN]
PRO Category
sequence
Parent
PR:000002308
Bcl-2-like protein 1
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000002385
Bcl-2-like protein 1 isoform 1, BCL2L1/iso:1
organism-sequence
PR:Q07817-1
Bcl-2-like protein 1 isoform 1 (human), hBCL2L1/iso:1
Yes
organism-sequence
PR:Q64373-1
Bcl-2-like protein 1 isoform Bcl-X(L) (mouse), mBCL2L1/iso:Bcl-X(L)
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:Q07817-1
hBCL2L1/iso:1
"A Bcl-2-like protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
acts_upstream_of_or_within
GO:0006915
apoptotic process
PMID:10949026
GO:0043066
negative regulation of apoptotic process
PMID:8596636
enables
NOT
GO:0005515
protein binding
with
PR:000028379
hBID/iso:1/Clv:1
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:O54918
Bcl2-interacting mediator of cell death (mouse)
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:Q07812
BAX
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:Q16611
apoptosis regulator BAK (human)
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:Q61337
Bad
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:Q92934-1
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:000026167
mBAD/iso:1/Phos:1
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:000026133
mBAD/iso:1/Phos:2
PMID:10949026
PR:Q64373-1
mBCL2L1/iso:Bcl-X(L)
Bcl-2-like protein 1 isoform Bcl-xL (mouse)
"A Bcl-2-like protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
acts_upstream_of_or_within
GO:0043066
negative regulation of apoptotic process
MGI:81233
;
PMID:8798158
GO:0043066
negative regulation of apoptotic process
MGI:81233
;
PMID:8798158
associated_with_disease_progression
DO:162
cancer
PMID:16403219
enables
GO:0005515
protein binding
with
PR:O08734
apoptosis regulator BAK (mouse)
MGI:3804133
;
PMID:16705087
GO:0046982
protein heterodimerization activity
MGI:82784
;
PMID:8798452