back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - natural resistance-associated macrophage protein 2
PR:000002993 - http://purl.obolibrary.org/obo/PR_000002993
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002993   
  PRO namenatural resistance-associated macrophage protein 2 
  Synonyms
PRO-Short-label: EXACT:SLC11A2
Gene-based: RELATED:DCT1 | DMT1 | NRAMP2 | OK/SW-cl.20
Other: EXACT:divalent cation transporter 1 | divalent metal transporter 1 | DMT-1 | NRAMP 2 | solute carrier family 11 member 2
  Definition"An NRAMP-like divalent ion transporter that is a translation product of the human SLC11A2 gene or a 1:1 ortholog thereof." [PRO:HJD] 
  PRO Categorygene 
  ParentPR:000002992 NRAMP-like divalent ion transporter
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence2                                                  Organism-Sequence 16                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARobj:967
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002993 natural resistance-associated macrophage protein 2, SLC11A2

organism-gene


PR:B3F8C5 NRAMP2 isoform 1 (chicken), chick-SLC11A2

organism-gene


PR:O54902 natural resistance-associated macrophage protein 2 (rat), rSLC11A2

organism-sequence


PR:O54902-1 natural resistance-associated macrophage protein 2 isoform r2 (rat), rSLC11A2/iso:r2

organism-sequence


PR:O54902-2 natural resistance-associated macrophage protein 2 isoform r1 (rat), rSLC11A2/iso:r1

organism-gene


PR:P49281 natural resistance-associated macrophage protein 2 (human), hSLC11A2

organism-sequence


PR:000063697 natural resistance-associated macrophage protein 2 sequence variant G212V (human), hSLC11A2/var:G212V

organism-sequence


PR:000063872 natural resistance-associated macrophage protein 2 sequence variant R416C (human), hSLC11A2/var:R416C

organism-sequence


PR:000064631 natural resistance-associated macrophage protein 2 sequence variant E399D (human), hSLC11A2/var:E399D

organism-sequence


PR:P49281-1 natural resistance-associated macrophage protein 2 isoform 2 (human), hSLC11A2/iso:2

organism-sequence


PR:P49281-2 natural resistance-associated macrophage protein 2 isoform 1 (human), hSLC11A2/iso:1

organism-sequence


PR:P49281-3 natural resistance-associated macrophage protein 2 isoform h3 (human), hSLC11A2/iso:h3

organism-sequence


PR:P49281-4 natural resistance-associated macrophage protein 2 isoform h4 (human), hSLC11A2/iso:h4

organism-sequence


PR:P49281-5 natural resistance-associated macrophage protein 2 isoform h5 (human), hSLC11A2/iso:h5

organism-modification


PR:000074463 natural resistance-associated macrophage protein 2 deaminated 1 (human), hSLC11A2/Deam:1

organism-modification


PR:000076056 natural resistance-associated macrophage protein 2 deaminated 2 (human), hSLC11A2/Deam:2

organism-modification


PR:000080800 natural resistance-associated macrophage protein 2 deaminated 3 (human), hSLC11A2/Deam:3

organism-gene


PR:P49282 natural resistance-associated macrophage protein 2 (mouse), mSLC11A2
Yes
organism-sequence


PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse), mSLC11A2/iso:2
Yes
organism-sequence


PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse), mSLC11A2/iso:1
Yes
organism-sequence


PR:P49282-3 natural resistance-associated macrophage protein 2 isoform m3 (mouse), mSLC11A2/iso:m3

organism-sequence


PR:P49282-4 natural resistance-associated macrophage protein 2 isoform m4 (mouse), mSLC11A2/iso:m4

organism-gene


PR:P49283 protein Malvolio (fruit fly), fly-SLC11A2

organism-sequence


PR:P49283-1 protein Malvolio isoform C (fruit fly), fly-SLC11A2/iso:C

organism-sequence


PR:P49283-2 protein Malvolio isoform A (fruit fly), fly-SLC11A2/iso:A

organism-gene


PR:Q869V1 metal transporter nramp1 homolog (Dictyostelium discoideum), Dicty-SLC11A2

sequence


PR:000002995 natural resistance-associated macrophage protein 2 isoform 1, SLC11A2/iso:1

organism-sequence


PR:P49281-2 natural resistance-associated macrophage protein 2 isoform 1 (human), hSLC11A2/iso:1

organism-sequence


PR:P49282-2 natural resistance-associated macrophage protein 2 isoform 1 (mouse), mSLC11A2/iso:1
Yes
sequence


PR:000002996 natural resistance-associated macrophage protein 2 isoform 2, SLC11A2/iso:2

organism-sequence


PR:P49281-1 natural resistance-associated macrophage protein 2 isoform 2 (human), hSLC11A2/iso:2

organism-sequence


PR:P49282-1 natural resistance-associated macrophage protein 2 isoform 2 (mouse), mSLC11A2/iso:2
Yes
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P49282 mSLC11A2
Dct1 | Dmt1 | Nramp2 | Slc11a2 | divalent cation transporter 1 (mouse) | divalent metal transporter 1 (mouse) | DMT-1 (mouse) | NRAMP 2 (mouse) | solute carrier family 11 member 2 (mouse)
"A natural resistance-associated macrophage protein 2 that is encoded in the genome of mouse." [OMA:P49282, PRO:DNx]		 acts_upstream_of_or_withinGO:0006778 porphyrin-containing compound metabolic process PMID:4404581
GO:0006826 iron ion transport PMID:807277
GO:0007611 learning or memory PMID:19211831
GO:0048813 dendrite morphogenesis PMID:19211831
GO:0048821 erythrocyte development PMID:15849611
GO:0060586 multicellular organismal-level iron ion homeostasis PMID:5070129
PR:P49282-1 mSLC11A2/iso:2
natural resistance-associated macrophage protein 2 isoform Non-IRE (mouse)
"A natural resistance-associated macrophage protein 2 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]		 acts_upstream_of_or_withinGO:0006824 cobalt ion transport MGI:3849744; PMID:10942769
GO:0006824 cobalt ion transport MGI:3849744; PMID:10942769
GO:0006824 cobalt ion transport MGI:3849744; PMID:10942769
GO:0006826 iron ion transport MGI:3849744; PMID:10942769
GO:0006826 iron ion transport MGI:3849744; PMID:10942769
GO:1902600 proton transmembrane transport MGI:3037617; PMID:15024413
enablesGO:0015078 proton transmembrane transporter activity MGI:3037617; PMID:15024413
GO:0015087 cobalt ion transmembrane transporter activity MGI:3849744; PMID:10942769
GO:0015087 cobalt ion transmembrane transporter activity MGI:3849744; PMID:10942769
GO:0015093 ferrous iron transmembrane transporter activity MGI:3849744; PMID:10942769
GO:0015093 ferrous iron transmembrane transporter activity MGI:3849744; PMID:10942769
located_inGO:0005886 plasma membrane MGI:3849744; PMID:10942769
GO:0005886 plasma membrane MGI:3849744; PMID:10942769
GO:0005886 plasma membrane MGI:3849744; PMID:10942769
GO:0009986 cell surface MGI:3695635; PMID:17097837
GO:0055037 recycling endosome MGI:3695780; PMID:16905747
GO:0055037 recycling endosome MGI:3695780; PMID:16905747
PR:P49282-2 mSLC11A2/iso:1
natural resistance-associated macrophage protein 2 isoform IRE (mouse)
"A natural resistance-associated macrophage protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]		 acts_upstream_of_or_withinGO:0006824 cobalt ion transport MGI:3603092; PMID:16142913
GO:0006826 iron ion transport MGI:3603092; PMID:16142913
GO:0033212 iron import into cell MGI:3037617; PMID:15024413
enablesGO:0005381 iron ion transmembrane transporter activity MGI:3603092; PMID:16142913
GO:0015087 cobalt ion transmembrane transporter activity MGI:3603092; PMID:16142913
GO:0015093 ferrous iron transmembrane transporter activity MGI:3037617; PMID:15024413
located_inGO:0005769 early endosome MGI:2667558; PMID:12724326
GO:0005886 plasma membrane MGI:2667558; PMID:12724326
GO:0005903 brush border MGI:3619154; PMID:11090085
GO:0005903 brush border MGI:3619154; PMID:11090085
GO:0012505 endomembrane system MGI:2667558; PMID:12724326