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Protein Ontology report - merlin
PR:000003020 - http://purl.obolibrary.org/obo/PR_000003020
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003020   
  PRO namemerlin 
  Synonyms
PRO-Short-label: EXACT:NF2
Gene-based: RELATED:Nf-2 | SCH
Other: EXACT:moesin-ezrin-radixin-like protein | neurofibromin-2 | schwannomerlin | schwannomin
  Definition"An erm protein that is a translation product of the human NF2 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001030
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence4                                                  Organism-Sequence 12                                        
         Modification5                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003020 merlin, NF2

organism-gene


PR:P35240 merlin (human), hNF2

organism-sequence


PR:P35240-1 merlin isoform 1 (human), hNF2/iso:1
Yes
organism-sequence


PR:P35240-10 merlin isoform h10 (human), hNF2/iso:h10

organism-sequence


PR:P35240-2 merlin isoform 3 (human), hNF2/iso:3

organism-sequence


PR:P35240-3 merlin isoform 2 (human), hNF2/iso:2
Yes
organism-sequence


PR:P35240-4 merlin isoform 4 (human), hNF2/iso:4
Yes
organism-sequence


PR:P35240-5 merlin isoform h5 (human), hNF2/iso:h5

organism-sequence


PR:P35240-6 merlin isoform h6 (human), hNF2/iso:h6

organism-sequence


PR:P35240-7 merlin isoform h7 (human), hNF2/iso:h7

organism-sequence


PR:P35240-8 merlin isoform h8 (human), hNF2/iso:h8

organism-sequence


PR:P35240-9 merlin isoform h9 (human), hNF2/iso:h9

organism-modification


PR:000045760 merlin phosphorylated 1 (human), hNF2/Phos:1

organism-modification


PR:000080467 merlin methylated 1 (human), hNF2/Me:1

organism-gene


PR:P46662 merlin (mouse), mNF2

organism-sequence


PR:P46662-1 merlin isoform 1 (mouse), mNF2/iso:1

organism-sequence


PR:P46662-2 merlin isoform 2 (mouse), mNF2/iso:2

organism-gene


PR:Q24564 moesin/ezrin/radixin homolog 2 (fruit fly), fly-NF2

sequence


PR:000003021 merlin isoform 1, NF2/iso:1

organism-sequence


PR:P35240-1 merlin isoform 1 (human), hNF2/iso:1
Yes
organism-sequence


PR:P46662-1 merlin isoform 1 (mouse), mNF2/iso:1

modification


PR:000003024 merlin isoform 1 phosphorylated form, NF2/iso:1/PhosRes+

modification


PR:000003025 merlin isoform 1 phosphorylated 1, NF2/iso:1/Phos:1

modification


PR:000003026 merlin isoform 1 phosphorylated 2, NF2/iso:1/Phos:2

sequence


PR:000003022 merlin isoform 2, NF2/iso:2

organism-sequence


PR:P35240-3 merlin isoform 2 (human), hNF2/iso:2
Yes
organism-sequence


PR:P46662-2 merlin isoform 2 (mouse), mNF2/iso:2

modification


PR:000003028 merlin isoform 2 phosphorylated form, NF2/iso:2/PhosRes+

modification


PR:000003029 merlin isoform 2 phosphorylated 1, NF2/iso:2/Phos:1

sequence


PR:000026545 merlin isoform 3, NF2/iso:3

organism-sequence


PR:P35240-2 merlin isoform 3 (human), hNF2/iso:3

sequence


PR:000026547 merlin isoform 4, NF2/iso:4

organism-sequence


PR:P35240-4 merlin isoform 4 (human), hNF2/iso:4
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P35240-1
hNF2/iso:1
 enablesGO:0005515 protein binding with PR:O14745 EBP50 (human) PMID:15467741
GO:0005515 protein binding with PR:Q9H204 EG1 PMID:15467741
located_inGO:0005634 nucleus PMID:20178741
PR:P35240-3
hNF2/iso:2
merlin isoform II (human)		 enablesGO:0005515 protein binding with PR:Q9H204 EG1 PMID:15467741
PR:P35240-4
hNF2/iso:4
merlin delE2/3 (human)		 enablesGO:0005515 protein binding with PR:P0DPB3-1 PMID:10669747