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Protein Ontology report - mitogen-activated protein kinase kinase kinase kinase 4
PR:000003043 - http://purl.obolibrary.org/obo/PR_000003043
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003043   
  PRO namemitogen-activated protein kinase kinase kinase kinase 4 
  Synonyms
PRO-Short-label: EXACT:MAP4K4
Gene-based: RELATED:HGK | KIAA0687 | NIK
Other: EXACT:HPK/GCK-like kinase HGK | MAPK/ERK kinase kinase kinase 4 | MEK kinase kinase 4 | MEKKK 4 | Nck-interacting kinase
  Definition"A protein that is a translation product of the human MAP4K4 gene or a 1:1 ortholog thereof." [PMID:16938849, PRO:AL] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 11                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2088
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003043 mitogen-activated protein kinase kinase kinase kinase 4, MAP4K4

organism-gene


PR:O95819 mitogen-activated protein kinase kinase kinase kinase 4 (human), hMAP4K4

organism-sequence


PR:O95819-1 mitogen-activated protein kinase kinase kinase kinase 4 isoform h1 (human), hMAP4K4/iso:h1

organism-sequence


PR:O95819-2 mitogen-activated protein kinase kinase kinase kinase 4 isoform h2 (human), hMAP4K4/iso:h2

organism-sequence


PR:O95819-3 mitogen-activated protein kinase kinase kinase kinase 4 isoform h3 (human), hMAP4K4/iso:h3

organism-sequence


PR:O95819-4 mitogen-activated protein kinase kinase kinase kinase 4 isoform h4 (human), hMAP4K4/iso:h4

organism-sequence


PR:O95819-5 mitogen-activated protein kinase kinase kinase kinase 4 isoform h5 (human), hMAP4K4/iso:h5

organism-sequence


PR:O95819-6 mitogen-activated protein kinase kinase kinase kinase 4 isoform h6 (human), hMAP4K4/iso:h6

organism-modification


PR:000048312 mitogen-activated protein kinase kinase kinase kinase 4, initiator methionine removed form (human), hMAP4K4/InitMet-

organism-modification


PR:000075673 mitogen-activated protein kinase kinase kinase kinase 4 hydroxylated 1 (human), hMAP4K4/Hy:1

organism-gene


PR:P97820 mitogen-activated protein kinase kinase kinase kinase 4 (mouse), mMAP4K4

organism-sequence


PR:P97820-1 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 (mouse), mMAP4K4/iso:1
Yes
organism-gene


PR:Q0WPH8 serine/threonine-protein kinase Nek5 (Arabidopsis thaliana), At-MAP4K4

organism-gene


PR:Q23356 serine/threonine-protein kinase mig-15 (worm), MAP4K4 (worm)

organism-sequence


PR:Q23356-1 serine/threonine-protein kinase mig-15 isoform c (worm), MAP4K4/iso:c (worm)

organism-sequence


PR:Q23356-2 serine/threonine-protein kinase mig-15 isoform a (worm), MAP4K4/iso:a (worm)

organism-sequence


PR:Q23356-3 serine/threonine-protein kinase mig-15 isoform b (worm), MAP4K4/iso:b (worm)

organism-sequence


PR:Q23356-4 serine/threonine-protein kinase mig-15 isoform d (worm), MAP4K4/iso:d (worm)

sequence


PR:000003044 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1, MAP4K4/iso:1

organism-sequence


PR:P97820-1 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 (mouse), mMAP4K4/iso:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P97820-1 mMAP4K4/iso:1

"A mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 that is encoded in the genome of mouse." [PRO:AL]		 acts_upstream_of_or_withinGO:0006468 protein phosphorylation PMID:16938849
GO:0010591 regulation of lamellipodium assembly PMID:16938849
enablesGO:0004674 protein serine/threonine kinase activity PMID:16938849
GO:0005515 protein binding PMID:16938849