Home
|
Linked Open Data
|
Browse
|
Search
|
Statistics
|
Download
RACE-PRO
PRO tracker
Community
PRO Consortium
Publications
Documentation
Protein Ontology report - Bcl2-associated agonist of cell death isoform 1 phosphorylated 2
PR:000003086 -
http://purl.obolibrary.org/obo/PR_000003086
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000003086
PRO name
Bcl2-associated agonist of cell death isoform 1 phosphorylated 2
Synonyms
PRO-Short-label
:
EXACT:
BAD/iso:1/Phos:2
Other
:
EXACT:
inactive BAD
Definition
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at the indicated Ser residues within each of two RxRxxSxP motifs, and within the RRxS motif located in the BH3 domain. Example:
UniProtKB:Q61337-1
, Ser-112/Ser-136/Ser-155,
MOD:00046
." [
PMID:10880354
,
PMID:10949026
, PRO:CNA, PRO:DAN, PRO:JAN]
Comment
Note: The RRxS motif site is the major PKA phosphorylation site. Phosphorylation on these residues favors binding to 14-3-3 proteins.
PRO Category
modification
Parent
PR:000003084
Bcl2-associated agonist of cell death isoform 1 phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
Back to top
Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000003086
Bcl2-associated agonist of cell death isoform 1 phosphorylated 2, BAD/iso:1/Phos:2
organism-modification
PR:000026133
Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse), mBAD/iso:1/Phos:2
Yes
Back to top
Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000026133
mBAD/iso:1/Phos:2
UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:JAN]
acts_upstream_of_or_within
GO:0043066
negative regulation of apoptotic process
PMID:10949026
enables
NOT
GO:0005515
protein binding
with
PR:000003237
fam:14-3-3
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:P63101-1
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:Q64373-1
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:Q07817-1
PMID:10949026