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Protein Ontology report - Bcl2-associated agonist of cell death isoform 1 phosphorylated 2
PR:000003086 - http://purl.obolibrary.org/obo/PR_000003086
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003086   
  PRO nameBcl2-associated agonist of cell death isoform 1 phosphorylated 2 
  Synonyms
PRO-Short-label: EXACT:BAD/iso:1/Phos:2
Other: EXACT:inactive BAD
  Definition"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at the indicated Ser residues within each of two RxRxxSxP motifs, and within the RRxS motif located in the BH3 domain. Example: UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:CNA, PRO:DAN, PRO:JAN] 
  CommentNote: The RRxS motif site is the major PKA phosphorylation site. Phosphorylation on these residues favors binding to 14-3-3 proteins. 
  PRO Categorymodification 
  ParentPR:000003084 Bcl2-associated agonist of cell death isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
modification



PR:000003086 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2, BAD/iso:1/Phos:2


organism-modification



PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse), mBAD/iso:1/Phos:2

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026133 mBAD/iso:1/Phos:2
UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:JAN]
acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:10949026
enablesNOT GO:0005515 protein binding with PR:000003237 fam:14-3-3 PMID:10949026
NOT GO:0005515 protein binding with PR:P63101-1 PMID:10949026
NOT GO:0005515 protein binding with PR:Q64373-1 PMID:10949026
NOT GO:0005515 protein binding with PR:Q07817-1 PMID:10949026