PRO Term |
GO Annotation |
Evidence |
PR:000025750 hCDKN1B/iso:1/Phos:2 UniProtKB:P46527-1, Tyr-88, MOD:00048 "A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 in human. Phosphorylation at this site promotes subsequent Cdk2-mediated phosphorylation at Thr-187. UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:JAN] |
acts_upstream_of_or_within | GO:0051318 G1 phase |
PMID:17254966 |
enables | decreased GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity relative to PR:000045370 hCDKN1B/iso:1/UnPhos:2 |
PMID:17254966 |
GO:0005515 protein binding with PR:P24385 B-cell lymphoma 1 protein (human) |
PMID:17254966 |
GO:0005515 protein binding with PR:P24864 CCNE |
PMID:17254966 |
GO:0005515 protein binding |
PMID:17254966 |
GO:0044877 protein-containing complex binding |
PMID:17254966 |
PR:000036634 hCDKN1B/iso:1/Phos:1 UniProtKB:P46527-1, Thr-157, MOD:00047 "A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 in human. UniProtKB:P46527-1, Thr-157, MOD:00047." [PMID:12244301, PMID:15057270, PRO:JAN] |
acts_upstream_of_or_within | GO:0008284 positive regulation of cell population proliferation |
PMID:12244301 |
enables | decreased GO:0005515 protein binding with PR:P31946 hYWHAB |
PMID:15057270 |
decreased GO:0005515 protein binding with PR:P61981 hYWHAG |
PMID:15057270 |
decreased GO:0005515 protein binding with PR:P62258 14-3-3E (human) |
PMID:15057270 |
decreased GO:0005515 protein binding with PR:P52294 hKPNA1 |
PMID:15057270 |
located_in | GO:0005737 cytoplasm |
PMID:15057270 |
GO:0005829 cytosol |
PMID:12244301 |