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Protein Ontology report - Bcl-2-binding component 3 isoform 1
PR:000003125 - http://purl.obolibrary.org/obo/PR_000003125
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003125   
  PRO nameBcl-2-binding component 3 isoform 1 
  Synonyms
PRO-Short-label: EXACT:BBC3/iso:1
Other: EXACT:puma-alpha
  Definition"A Bcl-2-binding component 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BXH1-1 or a 1:1 ortholog thereof." [PMID:11463391, PMID:11463392, PRO:JAN] 
  PRO Categorysequence 
  ParentPR:000003124 Bcl-2-binding component 3
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000003125 Bcl-2-binding component 3 isoform 1, BBC3/iso:1


organism-sequence



PR:Q99ML1-1 Bcl-2-binding component 3 isoform 1 (mouse), mBBC3/iso:1

Yes

organism-sequence



PR:Q9BXH1-1 Bcl-2-binding component 3 isoform 1 (human), hBBC3/iso:1

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q99ML1-1 mBBC3/iso:1

"A Bcl-2-binding component 3 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
enablesGO:0005515 protein binding with PR:P63168 8 kDa dynein light chain (mouse) PMID:10198631
PR:Q9BXH1-1 hBBC3/iso:1
Bcl-2-binding component 3 isoform PUMA alpha (human)
"A Bcl-2-binding component 3 isoform 1 that is encoded in the genome of human." [PRO:JAN]
acts_upstream_of_or_withinGO:0001836 release of cytochrome c from mitochondria PMID:11463392
GO:0006915 apoptotic process PMID:11463392
GO:0006915 apoptotic process PMID:11463392
enablesGO:0005515 protein binding with PR:P10415 BCL2 PMID:11463391
GO:0005515 protein binding with PR:Q07817-1 PMID:11463391
located_inGO:0005739 mitochondrion PMID:11463392
GO:0005739 mitochondrion PMID:11463392