back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - interferon regulatory factor 3 isoform 1
PR:000003257 - http://purl.obolibrary.org/obo/PR_000003257
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003257   
  PRO nameinterferon regulatory factor 3 isoform 1 
  Synonyms
PRO-Short-label: EXACT:IRF3/iso:1
  Definition"An interferon regulatory factor 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-1 or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000002045 interferon regulatory factor 3
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000003257 interferon regulatory factor 3 isoform 1, IRF3/iso:1

organism-sequence


PR:P70671-1 interferon regulatory factor 3 isoform 1 (mouse), mIRF3/iso:1
Yes
organism-modification


PR:000027097 interferon regulatory factor 3 isoform 1 phosphorylated 1 (mouse), mIRF3/iso:1/Phos:1

Yes
organism-sequence


PR:Q14653-1 interferon regulatory factor 3 isoform 1 (human), hIRF3/iso:1

organism-modification


PR:000025763 interferon regulatory factor 3 isoform 1 phosphorylated 1 (human), hIRF3/iso:1/Phos:1
Yes
Yes
organism-modification


PR:000045489 interferon regulatory factor 3 isoform 1 phosphorylated 2 (human), hIRF3/iso:1/Phos:2

Yes
modification


PR:000003259 interferon regulatory factor 3 isoform 1 phosphorylated form, IRF3/iso:1/PhosRes+

modification


PR:000003260 interferon regulatory factor 3 isoform 1 phosphorylated 1, IRF3/iso:1/Phos:1

organism-modification


PR:000025763 interferon regulatory factor 3 isoform 1 phosphorylated 1 (human), hIRF3/iso:1/Phos:1
Yes
Yes
organism-modification


PR:000027097 interferon regulatory factor 3 isoform 1 phosphorylated 1 (mouse), mIRF3/iso:1/Phos:1

Yes
organism-modification


PR:000045489 interferon regulatory factor 3 isoform 1 phosphorylated 2 (human), hIRF3/iso:1/Phos:2

Yes
Back to top
IRF3/iso:1 forms found in complexes   

IRF3/iso:1 Component
 Complexes
PR:000025763 hIRF3/iso:1/Phos:1 PR:000036002 IRF3-P:IRF3-P:KPNA4 complex (human)
PR:000027097 mIRF3/iso:1/Phos:1 PR:000027098 IRF3-P:IRF3-P complex (mouse)
PR:000036043 IRF3-P:p65 complex (mouse)
PR:000036047 IRF3-P:p65:ISRE complex (mouse)
PR:000045489 hIRF3/iso:1/Phos:2 PR:000027084 IRF3-P:IRF7-P complex (human)
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025763 hIRF3/iso:1/Phos:1
UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046 | IRF3-P (human)
"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:10805757, PRO:CNA]		 enablesGO:0005515 protein binding with PR:O14980 chromosome region maintenance 1 protein homolog (human) PMID:10805757
located_inGO:0005829 cytosol Reactome:REACT_7149
PR:P70671-1 mIRF3/iso:1

"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]		 located_inGO:0005737 cytoplasm MGI:3828224; PMID:18851954