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Protein Ontology report - phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2
PR:000003305 - http://purl.obolibrary.org/obo/PR_000003305
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003305   
  PRO namephosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 
  Synonyms
PRO-Short-label: EXACT:INPP5D/iso:2
  Definition"A phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ES52-2 or a 1:1 ortholog thereof." [PRO:HJD] 
  PRO Categorysequence 
  ParentPR:000003302 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000003305 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2, INPP5D/iso:2

organism-sequence


PR:Q9ES52-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse), mINPP5D/iso:2
Yes
organism-modification


PR:000036644 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1 (mouse), mINPP5D/iso:2/Phos:1
Yes
modification


PR:000003314 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated form, INPP5D/iso:2/PhosRes+

modification


PR:000003313 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1, INPP5D/iso:2/Phos:1

organism-modification


PR:000036644 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1 (mouse), mINPP5D/iso:2/Phos:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036644 mINPP5D/iso:2/Phos:1

"A phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1 in mouse." [PMID:8643691, PRO:HJD]		 enablesGO:0005515 protein binding with PR:P98083 mSHC1 PMID:8643691
PR:Q9ES52-2 mINPP5D/iso:2

"A phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]		 acts_upstream_of_or_withinGO:0008285 negative regulation of cell population proliferation MGI:85574; PMID:8890215
enablesGO:0004445 inositol-polyphosphate 5-phosphatase activity MGI:85578; PMID:8643691
GO:0017124 SH3 domain binding MGI:85578; PMID:8643691
GO:0034594 phosphatidylinositol trisphosphate phosphatase activity MGI:85574; PMID:8890215
GO:0051425 PTB domain binding MGI:85577; PMID:8654924