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Protein Ontology report - suppressor of fused homolog isoform 4
PR:000003327 - http://purl.obolibrary.org/obo/PR_000003327
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003327   
  PRO namesuppressor of fused homolog isoform 4 
  Synonyms
PRO-Short-label: EXACT:SUFU/iso:4
Other: EXACT:SU(FU)-XL
  Definition"A suppressor of fused homolog that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z0P7-4 or a 1:1 ortholog thereof." [PMID:10531011, PMID:11557033, PRO:HJD, UniProtKB:Q9Z0P7-4] 
  PRO Categorysequence 
  ParentPR:000003324 suppressor of fused homolog
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000003327 suppressor of fused homolog isoform 4, SUFU/iso:4

organism-sequence


PR:Q9Z0P7-4 suppressor of fused homolog isoform 4 (mouse), mSUFU/iso:4
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9Z0P7-4 mSUFU/iso:4
suppressor of fused homolog isoform SU(FU)-XL (mouse)
"A suppressor of fused homolog isoform 4 that is encoded in the genome of mouse." [PRO:HJD]		 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II MGI:1346364; PMID:10531011
GO:0045879 negative regulation of smoothened signaling pathway MGI:1346364; PMID:10531011
enablesGO:0005515 protein binding with PR:P10071 GLI3 MGI:1346364; PMID:10531011
GO:0005515 protein binding with PR:P47806 Gli MGI:1346364; PMID:10531011
GO:0005515 protein binding with PR:Q0VGT2 Gli2 MGI:1346364; PMID:10531011
located_inGO:0005737 cytoplasm MGI:1346364; PMID:10531011