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Protein Ontology report - E3 SUMO-protein ligase PIAS2 isoform 1
PR:000003437 -
http://purl.obolibrary.org/obo/PR_000003437
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000003437
PRO name
E3 SUMO-protein ligase PIAS2 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
PIAS2/iso:1
Other
:
EXACT:
PIASx-beta
Definition
"An E3 SUMO-protein ligase PIAS2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q8C5D8-1
or a 1:1 ortholog thereof." [
PMID:17623776
, PRO:HJD]
PRO Category
sequence
Parent
PR:000003436
E3 SUMO-protein ligase PIAS2
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
1
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000003437
E3 SUMO-protein ligase PIAS2 isoform 1, PIAS2/iso:1
organism-sequence
PR:Q8C5D8-1
E3 SUMO-protein ligase PIAS2 isoform 1 (mouse), mPIAS2/iso:1
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:Q8C5D8-1
mPIAS2/iso:1
E3 SUMO-protein ligase PIAS2 isoform Miz1 (mouse) | E3 SUMO-protein ligase PIAS2 isoform PIASx-beta (mouse)
"An E3 SUMO-protein ligase PIAS2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
acts_upstream_of_or_within
GO:0006351
DNA-templated transcription
MGI:894957
;
PMID:9256341
GO:0006357
regulation of transcription by RNA polymerase II
MGI:894957
;
PMID:9256341
GO:0016925
protein sumoylation
PMID:15767674
GO:0045667
regulation of osteoblast differentiation
MGI:3723333
;
PMID:17623776
GO:0045893
positive regulation of DNA-templated transcription
MGI:3723333
;
PMID:17623776
enables
GO:0003677
DNA binding
MGI:894957
;
PMID:9256341
GO:0005515
protein binding
with
PR:P29037
mTBP
PMID:16522640
GO:0005515
protein binding
PMID:16522640
GO:0019789
SUMO transferase activity
PMID:15767674
located_in
GO:0005634
nucleus
PMID:16522640
GO:0016604
nuclear body
MGI:3629292
;
PMID:16675951
