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Protein Ontology report - early growth response protein 2
PR:000003469 - http://purl.obolibrary.org/obo/PR_000003469
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003469   
  PRO nameearly growth response protein 2 
  Synonyms
PRO-Short-label: EXACT:EGR2
Gene-based: RELATED:Krox-20 | KROX20 | Zfp-25
Other: EXACT:AT591 | E3 SUMO-protein transferase ERG2 | EGR-2 | zinc finger protein Krox-20
  Definition"A protein that is a translation product of the human EGR2 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003469 early growth response protein 2, EGR2

organism-gene


PR:P08152 E3 SUMO-protein ligase EGR2 (mouse), mEGR2
Yes
organism-sequence


PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse), mEGR2/iso:Long
Yes
organism-sequence


PR:P08152-2 E3 SUMO-protein ligase EGR2 isoform Short (mouse), mEGR2/iso:Short
Yes
organism-gene


PR:P11161 E3 SUMO-protein ligase EGR2 (human), hEGR2

organism-sequence


PR:P11161-1 E3 SUMO-protein ligase EGR2 isoform Long (human), hEGR2/iso:Long

organism-sequence


PR:P11161-2 E3 SUMO-protein ligase EGR2 isoform Short (human), hEGR2/iso:Short

organism-gene


PR:P51774 E3 SUMO-protein ligase EGR2 (rat), rEGR2

organism-sequence


PR:P51774-1 E3 SUMO-protein ligase EGR2 isoform Long (rat), rEGR2/iso:Long

organism-sequence


PR:P51774-2 E3 SUMO-protein ligase EGR2 isoform Short (rat), rEGR2/iso:Short

organism-gene


PR:Q05159 early growth response protein 2b (zebrafish), z-EGR2

sequence


PR:000003470 early growth response protein 2 isoform Long, EGR2/iso:Long

organism-sequence


PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse), mEGR2/iso:Long
Yes
organism-sequence


PR:P11161-1 E3 SUMO-protein ligase EGR2 isoform Long (human), hEGR2/iso:Long

sequence


PR:000022018 early growth response protein 2 isoform Short, EGR2/iso:Short

organism-sequence


PR:P11161-2 E3 SUMO-protein ligase EGR2 isoform Short (human), hEGR2/iso:Short

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P08152 mEGR2
Egr-2 | Egr2 | Krox-20 | Zfp-25 | E3 SUMO-protein transferase ERG2 (mouse) | early growth response protein 2 (mouse) | EGR-2 (mouse) | zinc finger protein Krox-20 (mouse)
"An early growth response protein 2 that is encoded in the genome of mouse." [OMA:P08152, PRO:DNx]		 acts_upstream_of_or_withinGO:0006355 regulation of DNA-templated transcription PMID:16136673
GO:0006355 regulation of DNA-templated transcription PMID:16136673
GO:0007622 rhythmic behavior PMID:8893031
GO:0008045 motor neuron axon guidance PMID:9806922
GO:0014037 Schwann cell differentiation PMID:16136673
GO:0021569 rhombomere 3 development PMID:9806922
GO:0021612 facial nerve structural organization PMID:9806922
GO:0021660 rhombomere 3 formation PMID:7903221
GO:0021666 rhombomere 5 formation PMID:7903221
GO:0030278 regulation of ossification PMID:8565822
GO:0042552 myelination PMID:16136673
GO:0042552 myelination PMID:16136673
PR:P08152-1 mEGR2/iso:Long

"An early growth response protein 2 isoform Long that is encoded in the genome of mouse." [PRO:CNA]		 acts_upstream_of_or_withinGO:0007622 rhythmic behavior PMID:8893031
GO:0045944 positive regulation of transcription by RNA polymerase II PMID:8093858
enablesGO:0003677 DNA binding PMID:8093858; PMID:8895582
GO:0003700 DNA-binding transcription factor activity PMID:8093858
located_inGO:0005634 nucleus PMID:15282162
PR:P08152-2 mEGR2/iso:Short

"An E3 SUMO-protein ligase EGR2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08152-2." [PRO:DNx, UniProtKB:P08152]		 enablesGO:0005515 protein binding with PR:Q8C5D8-1 MGI:3629292; PMID:16675951
located_inGO:0005634 nucleus MGI:3629292; PMID:16675951