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Protein Ontology report - Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
PR:000004195 - http://purl.obolibrary.org/obo/PR_000004195
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004195   
  PRO nameArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 
  Synonyms
PRO-Short-label: EXACT:ARAP3
Gene-based: RELATED:CENTD3 | Drag1 | Kiaa4097
Other: EXACT:Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein 3 | centaurin-delta-3 | Cnt-d3 | dual specificity Rho- and Arf-GTPase-activating protein 1
  Definition"A protein that is a translation product of the human ARAP3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004195 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, ARAP3

organism-gene


PR:Q8R5G7 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (mouse), mARAP3

organism-sequence


PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse), mARAP3/iso:1
Yes
organism-sequence


PR:Q8R5G7-2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 2 (mouse), mARAP3/iso:2

organism-sequence


PR:Q8R5G7-3 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform m3 (mouse), mARAP3/iso:m3

organism-modification


PR:000072490 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 cysteinylated 1 (mouse), mARAP3/Cyst:1

organism-gene


PR:Q8WWN8 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (human), hARAP3

organism-sequence


PR:Q8WWN8-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (human), hARAP3/iso:1

organism-sequence


PR:Q8WWN8-2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform h2 (human), hARAP3/iso:h2

organism-modification


PR:000074770 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 methylated 1 (human), hARAP3/Me:1

organism-modification


PR:000077645 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 acetylated 1 (human), hARAP3/Ac:1

organism-modification


PR:000077705 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 cysteinylated 1 (human), hARAP3/Cyst:1

sequence


PR:000037352 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1, ARAP3/iso:1

organism-sequence


PR:Q8R5G7-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse), mARAP3/iso:1
Yes
organism-sequence


PR:Q8WWN8-1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (human), hARAP3/iso:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8R5G7-1 mARAP3/iso:1

"An Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 that is encoded in the genome of mouse." [PMID:15546919, PRO:HJD]		 acts_upstream_of_or_withinGO:0008360 regulation of cell shape MGI:3511766; PMID:15546919
GO:0030336 negative regulation of cell migration MGI:3511766; PMID:15546919
GO:0035021 negative regulation of Rac protein signal transduction MGI:3511766; PMID:15546919
GO:0035024 negative regulation of Rho protein signal transduction MGI:3511766; PMID:15546919
located_inGO:0001726 ruffle MGI:3511766; PMID:15546919
GO:0005737 cytoplasm MGI:3511766; PMID:15546919
GO:0030027 lamellipodium MGI:3511766; PMID:15546919