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Protein Ontology report - serine-protein kinase ATM
PR:000004427 - http://purl.obolibrary.org/obo/PR_000004427
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004427   
  PRO nameserine-protein kinase ATM 
  Synonyms
PRO-Short-label: EXACT:ATM
Other: EXACT:A-T mutated | A-T mutated homolog | ataxia telangiectasia mutated | ataxia telangiectasia mutated homolog
  Definition"A protein that is a translation product of the human ATM gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification3                                                  Organism-Modification 17                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1934
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004427 serine-protein kinase ATM, ATM

organism-gene


PR:O74630 serine/threonine-protein kinase tel1 (Schizosaccharomyces pombe 972h-), Spom972h-ATM

organism-gene


PR:Q13315 serine-protein kinase ATM (human), hATM
Yes
organism-sequence


PR:Q13315-1 serine-protein kinase ATM isoform 1 (human), hATM/iso:1

organism-modification


PR:000026217 serine-protein kinase ATM isoform 1 phosphorylated 1 (human), hATM/iso:1/Phos:1

organism-modification


PR:000035423 serine-protein kinase ATM phosphorylated 2 (human), hATM/Phos:2
Yes
organism-modification


PR:000035452 serine-protein kinase ATM unphosphorylated form (human), hATM/PhosRes-

organism-modification


PR:000045909 serine-protein kinase ATM phosphorylated 1 (human), hATM/Phos:1

organism-modification


PR:000046414 serine-protein kinase ATM acetylated 1 (human), hATM/Ac:1

organism-modification


PR:000064028 serine-protein kinase ATM acetylated and phosphorylated 1 (human), hATM/AcPhos:1

organism-modification


PR:000067880 serine-protein kinase ATM methylated 1 (human), hATM/Me:1

organism-modification


PR:000068526 serine-protein kinase ATM methylated 2 (human), hATM/Me:2

organism-modification


PR:000068580 serine-protein kinase ATM cysteinylated 1 (human), hATM/Cyst:1

organism-modification


PR:000069648 serine-protein kinase ATM deaminated 1 (human), hATM/Deam:1

organism-modification


PR:000070379 serine-protein kinase ATM cysteinylated 2 (human), hATM/Cyst:2

organism-modification


PR:000070631 serine-protein kinase ATM methylated 3 (human), hATM/Me:3

organism-modification


PR:000071620 serine-protein kinase ATM methylated 4 (human), hATM/Me:4

organism-modification


PR:000071881 serine-protein kinase ATM phosphorylated 3 (human), hATM/Phos:3

organism-modification


PR:000078947 serine-protein kinase ATM methylated 5 (human), hATM/Me:5

organism-modification


PR:000083733 serine-protein kinase ATM methylated 6 (human), hATM/Me:6

organism-gene


PR:Q5EAK6 serine/threonine-protein kinase ATM (fruit fly), fly-ATM

organism-gene


PR:Q62388 serine-protein kinase ATM (mouse), mATM

organism-modification


PR:000082002 serine-protein kinase ATM cysteinylated 1 (mouse), mATM/Cyst:1

sequence


PR:000026201 serine-protein kinase ATM isoform 1, ATM/iso:1

organism-sequence


PR:Q13315-1 serine-protein kinase ATM isoform 1 (human), hATM/iso:1

organism-modification


PR:000026217 serine-protein kinase ATM isoform 1 phosphorylated 1 (human), hATM/iso:1/Phos:1

modification


PR:000026203 serine-protein kinase ATM isoform 1 phosphorylated 1, ATM/iso:1/Phos:1

organism-modification


PR:000026217 serine-protein kinase ATM isoform 1 phosphorylated 1 (human), hATM/iso:1/Phos:1

modification


PR:000035422 serine-protein kinase ATM phosphorylated 2, ATM/Phos:2

organism-modification


PR:000035423 serine-protein kinase ATM phosphorylated 2 (human), hATM/Phos:2
Yes
modification


PR:000035451 serine-protein kinase ATM unphosphorylated form, ATM/PhosRes-

organism-modification


PR:000035452 serine-protein kinase ATM unphosphorylated form (human), hATM/PhosRes-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035423
hATM/Phos:2
UniProtKB:Q13315, Ser-1403/Ser-1981, MOD:00046		 acts_upstream_of_or_withinincreased GO:0031577 spindle checkpoint signaling relative to PR:000035452 hATM/PhosRes- PMID:22099307
enablesincreased GO:0004672 protein kinase activity relative to PR:000035452 hATM/PhosRes- PMID:22099307
located_inGO:0000779 condensed chromosome, centromeric region PMID:22099307
GO:0000922 spindle pole PMID:22099307
GO:0005694 chromosome PMID:22099307
GO:0030496 midbody PMID:22099307
GO:0051233 spindle midzone PMID:22099307
PR:Q13315
hATM
ATM | A-T mutated (human) | ataxia telangiectasia mutated (human)		 enablesGO:0004672 protein kinase activity PMID:22071147