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Protein Ontology report - mitotic checkpoint protein BUB3
PR:000004856 - http://purl.obolibrary.org/obo/PR_000004856
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004856   
  PRO namemitotic checkpoint protein BUB3 
  Synonyms
PRO-Short-label: EXACT:BUB3
Other: EXACT:WD repeat type I transmembrane protein A72.5
  Definition"A protein that is a translation product of the human BUB3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification2                                                  Organism-Modification 17                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004856 mitotic checkpoint protein BUB3, BUB3

organism-gene


PR:O42860 mitotic checkpoint protein bub3 (Schizosaccharomyces pombe 972h-), Spom972h-BUB3

Yes
organism-gene


PR:O43684 mitotic checkpoint protein BUB3 (human), hBUB3
Yes
Yes
organism-sequence


PR:O43684-1 mitotic checkpoint protein BUB3 isoform h1 (human), hBUB3/iso:h1

organism-sequence


PR:O43684-2 mitotic checkpoint protein BUB3 isoform 2 (human), hBUB3/iso:2

organism-modification


PR:000035437 mitotic checkpoint protein BUB3 phosphorylated 1 (human), hBUB3/Phos:1
Yes
organism-modification


PR:000035454 mitotic checkpoint protein BUB3 unphosphorylated form (human), hBUB3/PhosRes-

organism-modification


PR:000045593 mitotic checkpoint protein BUB3 phosphorylated 2 (human), hBUB3/Phos:2

organism-modification


PR:000071531 mitotic checkpoint protein BUB3 methylated 1 (human), hBUB3/Me:1

organism-modification


PR:000071980 mitotic checkpoint protein BUB3 cysteinylated 1 (human), hBUB3/Cyst:1

organism-modification


PR:000072028 mitotic checkpoint protein BUB3 cysteinylated 2 (human), hBUB3/Cyst:2

organism-modification


PR:000072190 mitotic checkpoint protein BUB3 methylated 2 (human), hBUB3/Me:2

organism-modification


PR:000072404 mitotic checkpoint protein BUB3 acetylated 1 (human), hBUB3/Ac:1

organism-modification


PR:000073832 mitotic checkpoint protein BUB3 methylated 3 (human), hBUB3/Me:3

organism-modification


PR:000074693 mitotic checkpoint protein BUB3 cysteinylated 3 (human), hBUB3/Cyst:3

organism-modification


PR:000079964 mitotic checkpoint protein BUB3 deaminated 1 (human), hBUB3/Deam:1

organism-modification


PR:000083767 mitotic checkpoint protein BUB3 hydroxylated 1 (human), hBUB3/Hy:1

organism-modification


PR:000083783 mitotic checkpoint protein BUB3 methylated 4 (human), hBUB3/Me:4

organism-modification


PR:000083859 mitotic checkpoint protein BUB3 deaminated 2 (human), hBUB3/Deam:2

organism-modification


PR:000084196 mitotic checkpoint protein BUB3 deaminated 3 (human), hBUB3/Deam:3

organism-modification


PR:000085371 mitotic checkpoint protein BUB3 cysteinylated 4 (human), hBUB3/Cyst:4

organism-gene


PR:P26449 cell cycle arrest protein BUB3 (yeast), yBUB3
Yes
Yes
organism-modification


PR:000035438 cell cycle arrest protein BUB3 phosphorylated 1 (yeast), yBUB3/Phos:1

organism-gene


PR:Q54DM1 mitotic checkpoint protein bub3 (Dictyostelium discoideum), Dicty-BUB3

organism-gene


PR:Q9WVA3 mitotic checkpoint protein BUB3 (mouse), mBUB3

organism-sequence


PR:Q9WVA3-1 mitotic checkpoint protein BUB3 isoform 1 (mouse), mBUB3/iso:1

organism-gene


PR:Q9XWH0 mitotic checkpoint protein bub-3 (worm), BUB3 (worm)

organism-gene


PR:Q9YGY3 mitotic checkpoint protein BUB3 (frog), frog-BUB3

Yes
organism-sequence


PR:Q9YGY3-1 mitotic checkpoint protein BUB3 isoform 1 (frog), frog-BUB3/iso:1

organism-sequence


PR:Q9YGY3-2 mitotic checkpoint protein BUB3 isoform 2 (frog), frog-BUB3/iso:2

sequence


PR:000038165 mitotic checkpoint protein BUB3 isoform 2, BUB3/iso:2

organism-sequence


PR:O43684-2 mitotic checkpoint protein BUB3 isoform 2 (human), hBUB3/iso:2

organism-sequence


PR:Q9WVA3-1 mitotic checkpoint protein BUB3 isoform 1 (mouse), mBUB3/iso:1

modification


PR:000035436 mitotic checkpoint protein BUB3 phosphorylated 1, BUB3/Phos:1

organism-modification


PR:000035437 mitotic checkpoint protein BUB3 phosphorylated 1 (human), hBUB3/Phos:1
Yes
organism-modification


PR:000035438 cell cycle arrest protein BUB3 phosphorylated 1 (yeast), yBUB3/Phos:1

modification


PR:000035453 mitotic checkpoint protein BUB3 unphosphorylated form, BUB3/PhosRes-

organism-modification


PR:000035454 mitotic checkpoint protein BUB3 unphosphorylated form (human), hBUB3/PhosRes-

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BUB3 forms found in complexes   

BUB3 Component
 Complexes
PR:O42860 Spom972h-BUB3 PR:000035569
PR:O43684 hBUB3 PR:000035511^P000035563^P000035564^P000035567^P000035576
PR:P26449 yBUB3 PR:000035565
PR:Q9YGY3 frog-BUB3 PR:000035512
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035437
hBUB3/Phos:1
UniProtKB:O43684, Ser-18, MOD:00046		 acts_upstream_of_or_withinincreased GO:0012501 programmed cell death relative to PR:000035454 hBUB3/PhosRes- PMID:20057499
PR:O43684
hBUB3
BUB3		 enablesGO:0005515 protein binding with PR:O15350-1 PMID:10198256
GO:0005515 protein binding with PR:O15350-2 PMID:10198256
GO:0005515 protein binding with PR:O15350-3 PMID:10198256
GO:0005515 protein binding with PR:O15350-5 PMID:10198256
GO:0005515 protein binding with PR:O43683 BUB1 PMID:10198256
GO:0005515 protein binding with PR:O60566 BUB1B PMID:10198256
GO:0005515 protein binding with PR:P25054 APC PMID:10198256
GO:0005515 protein binding with PR:Q12834 CDC20 PMID:10198256
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:10198256
GO:0005515 protein binding with PR:Q9Y6D9 hMAD1 PMID:10198256
located_inGO:0000776 kinetochore PMID:11283619
PR:P26449
yBUB3
BUB3 | OR26.16 | YOR026W		 acts_upstream_of_or_withinGO:0006974 DNA damage response PMID:15514023
enablesGO:0005515 protein binding with PR:000035536 UniProtKB:P53148, Thr-149/Thr-172/Thr-235, MOD:00047 PMID:22521787
located_inGO:0000776 kinetochore PMID:22521787