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Protein Ontology report - F-actin-capping protein subunit beta
PR:000005032 - http://purl.obolibrary.org/obo/PR_000005032
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005032   
  PRO nameF-actin-capping protein subunit beta 
  Synonyms
PRO-Short-label: EXACT:CAPZB
Gene-based: RELATED:Cappb1
Other: EXACT:CapZ beta
  Definition"A protein that is a translation product of the human CAPZB gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 10                                        
         Sequence3                                                  Organism-Sequence 8                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000005032 F-actin-capping protein subunit beta, CAPZB

organism-gene


PR:P13021 F-actin-capping protein subunit beta (Dictyostelium discoideum), Dicty-CAPZB

organism-gene


PR:P13517 F-actin-capping protein subunit beta (yeast), yCAPZB

organism-gene


PR:P14315 F-actin-capping protein subunit beta isoforms 1 and 2 (chicken), chick-CAPZB

organism-sequence


PR:P14315-1 F-actin-capping protein subunit beta isoforms 1 and 2 isoform 1 (chicken), chick-CAPZB/iso:1

organism-sequence


PR:P14315-2 F-actin-capping protein subunit beta isoforms 1 and 2 isoform 2 (chicken), chick-CAPZB/iso:2

organism-gene


PR:P34686 F-actin-capping protein subunit beta (worm), CAPZB (worm)

organism-gene


PR:P47756 F-actin-capping protein subunit beta (human), hCAPZB

organism-sequence


PR:P47756-1 F-actin-capping protein subunit beta isoform h2 (human), hCAPZB/iso:h2

organism-sequence


PR:P47756-2 F-actin-capping protein subunit beta isoform h1 (human), hCAPZB/iso:h1

organism-sequence


PR:P47756-3 F-actin-capping protein subunit beta isoform h3 (human), hCAPZB/iso:h3

organism-modification


PR:000046565 F-actin-capping protein subunit beta, initiator methionine removed form (human), hCAPZB/InitMet-

organism-modification


PR:000066575 F-actin-capping protein subunit beta methylated 1 (human), hCAPZB/Me:1

organism-gene


PR:P47757 F-actin-capping protein subunit beta (mouse), mCAPZB

organism-sequence


PR:P47757-1 F-actin-capping protein subunit beta isoform 1 (mouse), mCAPZB/iso:1
Yes
organism-sequence


PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse), mCAPZB/iso:2
Yes
Yes
organism-sequence


PR:P47757-4 F-actin-capping protein subunit beta isoform Capzb3 (mouse), mCAPZB/iso:Capzb3
Yes
organism-gene


PR:P48603 F-actin-capping protein subunit beta (fruit fly), fly-CAPZB

organism-gene


PR:Q5XI32 F-actin-capping protein subunit beta (rat), rCAPZB

organism-gene


PR:Q9HGP5 F-actin-capping protein subunit beta (Schizosaccharomyces pombe 972h-), Spom972h-CAPZB

organism-gene


PR:Q9M9G7 probable F-actin-capping protein subunit beta (Arabidopsis thaliana), At-CAPZB

sequence


PR:000035824 F-actin-capping protein subunit beta isoform 1, CAPZB/iso:1

organism-sequence


PR:P47757-1 F-actin-capping protein subunit beta isoform 1 (mouse), mCAPZB/iso:1
Yes
sequence


PR:000035826 F-actin-capping protein subunit beta isoform 2, CAPZB/iso:2

organism-sequence


PR:P47757-2 F-actin-capping protein subunit beta isoform 2 (mouse), mCAPZB/iso:2
Yes
Yes
sequence


PR:000035828 F-actin-capping protein subunit beta isoform Capzb3, CAPZB/iso:Capzb3

organism-sequence


PR:P47757-4 F-actin-capping protein subunit beta isoform Capzb3 (mouse), mCAPZB/iso:Capzb3
Yes
modification


PR:000019237 F-actin-capping protein subunit beta, initiator methionine removed form, CAPZB/InitMet-

organism-modification


PR:000046565 F-actin-capping protein subunit beta, initiator methionine removed form (human), hCAPZB/InitMet-

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CAPZB forms found in complexes   

CAPZB Component
 Complexes
PR:P47757ZDASHZ2 mCAPZB/iso:2 PR:000035900 F-actin capping protein complex alpha-1 beta-2 (mouse)
PR:000035901 F-actin capping protein complex alpha-2 beta-2 (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P47757-1 mCAPZB/iso:1
CAPZ beta 1 (mouse) | CAPZ beta-1 (mouse) | CAPZB1 (mouse)
"An F-actin-capping protein subunit beta isoform 1 that is encoded in the genome of mouse." [PMID:10601341, PRO:KRC]		 acts_upstream_of_or_withinGO:0055001 muscle cell development MGI:1350695; PMID:10601341
GO:0090036 regulation of protein kinase C signaling MGI:3777904; PMID:12089068
located_inGO:0030018 Z disc MGI:68935; PMID:7929588
GO:0030018 Z disc MGI:68935; PMID:7929588
PR:P47757-2 mCAPZB/iso:2
CAPZ beta 2 (mouse) | CAPZ beta-2 (mouse) | CAPZB2 (mouse)
"An F-actin-capping protein subunit beta isoform 2 that is encoded in the genome of mouse." [PMID:10601341, PRO:KRC]		 acts_upstream_of_or_withinGO:0030032 lamellipodium assembly MGI:4397629; PMID:19806181
GO:0031115 negative regulation of microtubule polymerization MGI:4397629; PMID:19806181
GO:0031175 neuron projection development MGI:4397629; PMID:19806181
GO:0051016 barbed-end actin filament capping MGI:3758397; PMID:17656356
GO:0055001 muscle cell development MGI:1350695; PMID:10601341
enablescontributes_to GO:0005515 protein binding with PR:Q91YR1 mTWF1 MGI:3773286; PMID:11604420
GO:0048487 beta-tubulin binding MGI:4397629; PMID:19806181
contributes_to GO:0051015 actin filament binding MGI:3758397; PMID:17656356
located_inGO:0008290 F-actin capping protein complex MGI:4397629; PMID:19806181
GO:0008290 F-actin capping protein complex with PR:P47754 Cappa2 MGI:4397629; PMID:19806181
GO:0014704 intercalated disc MGI:68935; PMID:7929588
GO:0014704 intercalated disc MGI:68935; PMID:7929588
PR:P47757-4 mCAPZB/iso:Capzb3
Capzb isoform 3 (mouse) | Capzb3 (mouse)
"An F-actin-capping protein subunit beta isoform Capzb3 that is encoded in the genome of mouse." [PMID:19341723, PRO:KRC]		 located_incolocalizes_with GO:0001669 acrosomal vesicle MGI:3848085; PMID:19341723