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Protein Ontology report - kinetochore scaffold 1
PR:000005050 - http://purl.obolibrary.org/obo/PR_000005050
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005050   
  PRO namekinetochore scaffold 1 
  Synonyms
PRO-Short-label: EXACT:KNL1
Gene-based: RELATED:CASC5 | KIAA1570
Other: EXACT:AF15q14 | ALL1-fused gene from chromosome 15q14 | blinkin | Bub-linking kinetochore protein | cancer susceptibility candidate gene 5 protein | cancer susceptibility candidate gene 5 protein homolog | cancer/testis antigen 29 | CT29 | kinetochore-null protein 1 | protein CASC5 | protein D40/AF15q14
  Definition"A protein that is a translation product of the human KNL1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification2                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000005050 kinetochore scaffold 1, KNL1

organism-gene


PR:D3Z896 protein LOC100911204 (rat), rKNL1

organism-gene


PR:Q66JQ7 kinetochore scaffold 1 (mouse), mKNL1

organism-gene


PR:Q8NG31 kinetochore scaffold 1 (human), hKNL1
Yes
organism-sequence


PR:Q8NG31-1 kinetochore scaffold 1 isoform 1 (human), hKNL1/iso:1

organism-sequence


PR:Q8NG31-2 kinetochore scaffold 1 isoform 2 (human), hKNL1/iso:2

organism-modification


PR:000035558 kinetochore scaffold 1 isoform 2 phosphorylated 1 (human), hKNL1/iso:2/Phos:1
Yes
organism-modification


PR:000035560 kinetochore scaffold 1 isoform 2 unphosphorylated form (human), hKNL1/iso:2/PhosRes-

organism-sequence


PR:Q8NG31-3 kinetochore scaffold 1 isoform h3 (human), hKNL1/iso:h3

organism-sequence


PR:Q8NG31-4 kinetochore scaffold 1 isoform h4 (human), hKNL1/iso:h4

organism-modification


PR:000071007 kinetochore scaffold 1 methylated 1 (human), hKNL1/Me:1

organism-modification


PR:000071490 kinetochore scaffold 1 cysteinylated 1 (human), hKNL1/Cyst:1

organism-modification


PR:000077771 kinetochore scaffold 1 phosphorylated 1 (human), hKNL1/Phos:1

organism-modification


PR:000083702 kinetochore scaffold 1 deaminated 1 (human), hKNL1/Deam:1

sequence


PR:000035553 kinetochore scaffold 1 isoform 1, KNL1/iso:1

organism-sequence


PR:Q8NG31-1 kinetochore scaffold 1 isoform 1 (human), hKNL1/iso:1

sequence


PR:000035555 kinetochore scaffold 1 isoform 2, KNL1/iso:2

organism-sequence


PR:Q8NG31-2 kinetochore scaffold 1 isoform 2 (human), hKNL1/iso:2

organism-modification


PR:000035558 kinetochore scaffold 1 isoform 2 phosphorylated 1 (human), hKNL1/iso:2/Phos:1
Yes
organism-modification


PR:000035560 kinetochore scaffold 1 isoform 2 unphosphorylated form (human), hKNL1/iso:2/PhosRes-

modification


PR:000035557 kinetochore scaffold 1 isoform 2 phosphorylated 1, KNL1/iso:2/Phos:1

organism-modification


PR:000035558 kinetochore scaffold 1 isoform 2 phosphorylated 1 (human), hKNL1/iso:2/Phos:1
Yes
modification


PR:000035559 kinetochore scaffold 1 isoform 2 unphosphorylated form, KNL1/iso:2/PhosRes-

organism-modification


PR:000035560 kinetochore scaffold 1 isoform 2 unphosphorylated form (human), hKNL1/iso:2/PhosRes-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035558
hKNL1/iso:2/Phos:1
UniProtKB:Q8NG31-2, Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046		 acts_upstream_of_or_withinincreased GO:0034501 protein localization to kinetochore relative to PR:000035560 hKNL1/iso:2/PhosRes- PMID:22660415
PR:Q8NG31
hKNL1
CASC5 | KIAA1570 | KNL1 | AF15q14 (human) | ALL1-fused gene from chromosome 15q14 protein (human) | blinkin (human) | Bub-linking kinetochore protein (human) | cancer susceptibility candidate gene 5 protein (human) | cancer/testis antigen 29 (human) | CT29 (human) | kinetochore-null protein 1 (human) | protein CASC5 (human) | protein D40/AF15q14 (human)		 enablesGO:0005515 protein binding with PR:O14777 HEC BioGRID:BG-697221
GO:0005515 protein binding with PR:O43683 BUB1 BioGRID:BG-697221
GO:0005515 protein binding with PR:O60566 BUB1B BioGRID:BG-697221
located_inGO:0000776 kinetochore PMID:20624902