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Protein Ontology report - centromere-associated protein E
PR:000005326 - http://purl.obolibrary.org/obo/PR_000005326
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005326   
  PRO namecentromere-associated protein E 
  Synonyms
PRO-Short-label: EXACT:CENPE
Other: EXACT:CENP-E | centromere protein E | KIF10 | kinesin superfamily protein 10 | kinesin-related protein CENPE | motor domain of KIF10
  Definition"A protein that is a translation product of the human CENPE gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000005326 centromere-associated protein E, CENPE

organism-gene


PR:O42263 centromere-associated protein E (frog), frog-CENPE

organism-gene


PR:P34367 uncharacterized protein C50C3.2 (worm), CENPE (worm)

organism-gene


PR:Q02224 centromere-associated protein E (human), hCENPE
Yes
organism-sequence


PR:Q02224-1 centromere-associated protein E isoform h1 (human), hCENPE/iso:h1

organism-sequence


PR:Q02224-3 centromere-associated protein E isoform h3 (human), hCENPE/iso:h3

organism-modification


PR:000065456 centromere-associated protein E deaminated 1 (human), hCENPE/Deam:1

organism-modification


PR:000072868 centromere-associated protein E phosphorylated 1 (human), hCENPE/Phos:1

organism-modification


PR:000077661 centromere-associated protein E deaminated 2 (human), hCENPE/Deam:2

organism-modification


PR:000080776 centromere-associated protein E cysteinylated 1 (human), hCENPE/Cyst:1

organism-modification


PR:000082966 centromere-associated protein E methylated 1 (human), hCENPE/Me:1

organism-gene


PR:Q27IK7 kinesin-like protein KIN-12C (Arabidopsis thaliana), At-CENPE

organism-gene


PR:Q54NP8 kinesin-related protein 4 (Dictyostelium discoideum), Dicty-CENPE

organism-gene


PR:Q6RT24 centromere-associated protein E (mouse), mCENPE

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q02224 hCENPE
CENPE | CENP-E (human) | centromere protein E (human) | kinesin-7 (human) | kinesin-related protein CENPE (human)
"A centromere-associated protein E that is encoded in the genome of human." [PMID:12719470, PMID:15592459, PMID:17785528, PRO:KER]		 acts_upstream_of_or_withinGO:0033674 positive regulation of kinase activity PMID:22801780
GO:0034501 protein localization to kinetochore PMID:17785528
GO:0051310 metaphase chromosome alignment PMID:15592459
enablesGO:0005515 protein binding with PR:O60566 BUB1B BioGRID:BG-545452; IntAct:EBI-1646673
GO:0005515 protein binding with PR:P49454 AH antigen (human) BioGRID:BG-545452; IntAct:EBI-1646673
GO:0005515 protein binding with PR:Q9BZD4 CDCA1 BioGRID:BG-545452; IntAct:EBI-1646673
located_inGO:0000776 kinetochore PMID:12719470