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Protein Ontology report - catechol O-methyltransferase
PR:000005731 - http://purl.obolibrary.org/obo/PR_000005731
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005731   
  PRO namecatechol O-methyltransferase 
  Synonyms
PRO-Short-label: EXACT:COMT
Gene-based: RELATED:Comt1
  Definition"A protein that is a translation product of the human COMT gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence2                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2472
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000005731 catechol O-methyltransferase, COMT

organism-gene


PR:F4ZGF2 catechol O-methyltransferase A (zebrafish), z-COMT

organism-sequence


PR:F4ZGF2-1 catechol O-methyltransferase A isoform 1 (zebrafish), z-COMT/iso:1

organism-sequence


PR:F4ZGF2-2 catechol O-methyltransferase A isoform 2 (zebrafish), z-COMT/iso:2

organism-gene


PR:O42898 probable catechol O-methyltransferase 1 (Schizosaccharomyces pombe 972h-), Spom972h-COMT

organism-gene


PR:O88587 catechol O-methyltransferase (mouse), mCOMT

organism-sequence


PR:O88587-1 catechol O-methyltransferase isoform 1 (mouse), mCOMT/iso:1
Yes
organism-sequence


PR:O88587-2 catechol O-methyltransferase isoform 2 (mouse), mCOMT/iso:2
Yes
organism-gene


PR:P21964 catechol O-methyltransferase (human), hCOMT

organism-sequence


PR:P21964-1 catechol O-methyltransferase isoform Membrane-bound (human), hCOMT/iso:Membrane-bound

organism-sequence


PR:P21964-2 catechol O-methyltransferase isoform Soluble (human), hCOMT/iso:Soluble

organism-gene


PR:P22734 catechol O-methyltransferase (rat), rCOMT

organism-sequence


PR:P22734-1 catechol O-methyltransferase isoform Membrane-bound (rat), rCOMT/iso:Membrane-bound

organism-sequence


PR:P22734-2 catechol O-methyltransferase isoform Soluble (rat), rCOMT/iso:Soluble

sequence


PR:000025997 catechol O-methyltransferase isoform 1, COMT/iso:1

organism-sequence


PR:O88587-1 catechol O-methyltransferase isoform 1 (mouse), mCOMT/iso:1
Yes
organism-sequence


PR:P21964-1 catechol O-methyltransferase isoform Membrane-bound (human), hCOMT/iso:Membrane-bound

sequence


PR:000025999 catechol O-methyltransferase isoform 2, COMT/iso:2

organism-sequence


PR:O88587-2 catechol O-methyltransferase isoform 2 (mouse), mCOMT/iso:2
Yes
organism-sequence


PR:P21964-2 catechol O-methyltransferase isoform Soluble (human), hCOMT/iso:Soluble

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O88587-1
mCOMT/iso:1
MB-COMT (mouse) | membrane bound COMT		 acts_upstream_of_or_withinGO:0042417 dopamine metabolic process MGI:4830461; PMID:19930170
located_inNOT GO:0005886 plasma membrane MGI:4822307; PMID:20374420
PR:O88587-2
mCOMT/iso:2
s-COMT (mouse) | soluble COMT (mouse)		 acts_upstream_of_or_withinGO:0009712 catechol-containing compound metabolic process MGI:4830461; PMID:19930170
GO:0042417 dopamine metabolic process MGI:4830461; PMID:19930170
enablesGO:0016206 catechol O-methyltransferase activity MGI:4830461; PMID:19930170