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Protein Ontology report - dual specificity mitogen-activated protein kinase kinase 2
PR:000010126 - http://purl.obolibrary.org/obo/PR_000010126
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010126   
  PRO namedual specificity mitogen-activated protein kinase kinase 2 
  Synonyms
PRO-Short-label: EXACT:MAP2K2
Gene-based: RELATED:MEK2 | MKK2 | PRKMK2
Other: EXACT:ERK activator kinase 2 | MAP kinase kinase 2 | MAPK/ERK kinase 2 | MAPKK 2 | MEK 2
  Definition"A protein that is a translation product of the human MAP2K2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 9                                        
         Modification1                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2063
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000010126 dual specificity mitogen-activated protein kinase kinase 2, MAP2K2

organism-gene


PR:P36506 dual specificity mitogen-activated protein kinase kinase 2 (rat), rMAP2K2

organism-sequence


PR:P36506-1 dual specificity mitogen-activated protein kinase kinase 2 isoform 1 (rat), rMAP2K2/iso:1

organism-gene


PR:P36507 dual specificity mitogen-activated protein kinase kinase 2 (human), hMAP2K2

organism-sequence


PR:000060373 dual specificity mitogen-activated protein kinase kinase 2 sequence variant V35M (human), hMAP2K2/var:V35M

organism-sequence


PR:000060463 dual specificity mitogen-activated protein kinase kinase 2 sequence variant F57C (human), hMAP2K2/var:F57C

organism-sequence


PR:000060542 dual specificity mitogen-activated protein kinase kinase 2 sequence variant C125S (human), hMAP2K2/var:C125S

organism-sequence


PR:000060802 dual specificity mitogen-activated protein kinase kinase 2 sequence variant P128Q (human), hMAP2K2/var:P128Q

organism-sequence


PR:000061456 dual specificity mitogen-activated protein kinase kinase 2 sequence variant N126D (human), hMAP2K2/var:N126D

organism-sequence


PR:000063141 dual specificity mitogen-activated protein kinase kinase 2 sequence variant Y134C (human), hMAP2K2/var:Y134C

organism-sequence


PR:000063413 dual specificity mitogen-activated protein kinase kinase 2 sequence variant L46F (human), hMAP2K2/var:L46F

organism-sequence


PR:P36507-1 dual specificity mitogen-activated protein kinase kinase 2 isoform 1 (human), hMAP2K2/iso:1

organism-modification


PR:000027057 dual specificity mitogen-activated protein kinase kinase 2 autophosphorylated form (human), hMAP2K2/Phos:auto
Yes
organism-modification


PR:000061003 dual specificity mitogen-activated protein kinase kinase 2 phosphoserine and phosphothreonine form (human), hMAP2K2/pSerThr+

organism-modification


PR:000048296 dual specificity mitogen-activated protein kinase kinase 2 phosphorylated 2 (human), hMAP2K2/Phos:2

organism-modification


PR:000079434 dual specificity mitogen-activated protein kinase kinase 2 methylated 1 (human), hMAP2K2/Me:1

organism-gene


PR:Q63932 dual specificity mitogen-activated protein kinase kinase 2 (mouse), mMAP2K2

organism-gene


PR:Q90891 dual specificity mitogen-activated protein kinase kinase 2 (chicken), chick-MAP2K2

sequence


PR:000039362 dual specificity mitogen-activated protein kinase kinase 2 isoform 1, MAP2K2/iso:1

organism-sequence


PR:P36506-1 dual specificity mitogen-activated protein kinase kinase 2 isoform 1 (rat), rMAP2K2/iso:1

organism-sequence


PR:P36507-1 dual specificity mitogen-activated protein kinase kinase 2 isoform 1 (human), hMAP2K2/iso:1

modification


PR:000027056 dual specificity mitogen-activated protein kinase kinase 2 autophosphorylated form, MAP2K2/Phos:auto

organism-modification


PR:000027057 dual specificity mitogen-activated protein kinase kinase 2 autophosphorylated form (human), hMAP2K2/Phos:auto
Yes
organism-modification


PR:000061003 dual specificity mitogen-activated protein kinase kinase 2 phosphoserine and phosphothreonine form (human), hMAP2K2/pSerThr+

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027057
hMAP2K2/Phos:auto
human phospho-MEK2		 enablesGO:0004674 protein serine/threonine kinase activity PMID:8388392
located_inGO:0005829 cytosol Reactome:REACT_3571