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Protein Ontology report - induced myeloid leukemia cell differentiation protein Mcl-1
PR:000010240 - http://purl.obolibrary.org/obo/PR_000010240
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010240   
  PRO nameinduced myeloid leukemia cell differentiation protein Mcl-1 
  Synonyms
PRO-Short-label: EXACT:MCL1
Gene-based: RELATED:BCL2L3
Other: EXACT:Bcl-2-like protein 3 | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | mcl1/EAT
  Definition"A protein that is a translation product of the human MCL1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2847
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000010240 induced myeloid leukemia cell differentiation protein Mcl-1, MCL1

organism-gene


PR:P97287 induced myeloid leukemia cell differentiation protein Mcl-1 homolog (mouse), mMCL1

organism-sequence


PR:P97287-1 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 (mouse), mMCL1/iso:1
Yes
organism-modification


PR:000026225 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 (mouse), mMCL1/iso:1/Clv:1
Yes
organism-sequence


PR:P97287-2 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 (mouse), mMCL1/iso:2
Yes
organism-gene


PR:Q07820 induced myeloid leukemia cell differentiation protein Mcl-1 (human), hMCL1

organism-sequence


PR:Q07820-1 induced myeloid leukemia cell differentiation protein Mcl-1 isoform h1 (human), hMCL1/iso:h1

organism-sequence


PR:Q07820-2 induced myeloid leukemia cell differentiation protein Mcl-1 isoform h2 (human), hMCL1/iso:h2

organism-modification


PR:000065743 induced myeloid leukemia cell differentiation protein Mcl-1 deaminated 1 (human), hMCL1/Deam:1

organism-modification


PR:000083008 induced myeloid leukemia cell differentiation protein Mcl-1 deaminated 2 (human), hMCL1/Deam:2

organism-gene


PR:Q9Z1P3 induced myeloid leukemia cell differentiation protein Mcl-1 homolog (rat), rMCL1

sequence


PR:000026005 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1, MCL1/iso:1

organism-sequence


PR:P97287-1 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 (mouse), mMCL1/iso:1
Yes
organism-modification


PR:000026225 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 (mouse), mMCL1/iso:1/Clv:1
Yes
modification


PR:000026224 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1, MCL1/iso:1/Clv:1

organism-modification


PR:000026225 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 (mouse), mMCL1/iso:1/Clv:1
Yes
sequence


PR:000026007 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2, MCL1/iso:2

organism-sequence


PR:P97287-2 induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 (mouse), mMCL1/iso:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026225 mMCL1/iso:1/Clv:1
UniProtKB:P97287-1, 34-331
"An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 cleaved 1 in mouse. It lacks the N-terminal portion encompassing 33 amino acids. This form is generated by cleavage within the mitochondrial matrix. UniProtKB:P97287-1, 34-331." [PMID:20627101, PRO:HJD]		 located_inGO:0005759 mitochondrial matrix MGI:4822083; PMID:20627101
PR:P97287-1 mMCL1/iso:1
MCL-1L (mouse)
"An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 that is encoded in the genome of mouse." [PMID:9655929, PRO:HJD]		 acts_upstream_of_or_withinGO:0008637 apoptotic mitochondrial changes MGI:4421270; PMID:19919825
located_inGO:0005739 mitochondrion MGI:4421270; PMID:19919825
PR:P97287-2 mMCL1/iso:2
MCL-1V (mouse)
"An induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2 that is encoded in the genome of mouse." [PMID:19919825, PRO:HJD]		 acts_upstream_of_or_withinGO:0008637 apoptotic mitochondrial changes MGI:4421270; PMID:19919825
located_inGO:0005739 mitochondrion MGI:4421270; PMID:19919825