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Protein Ontology report - retinoic acid receptor alpha
PR:000013736 - http://purl.obolibrary.org/obo/PR_000013736
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000013736   
  PRO nameretinoic acid receptor alpha 
  Synonyms
PRO-Short-label: EXACT:RARA
Gene-based: RELATED:NR1B1
Other: EXACT:nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARalpha
  Definition"A protein that is a translation product of the human RARA gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 7                                        
         Modification1                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:590
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000013736 retinoic acid receptor alpha, RARA

organism-gene


PR:P10276 retinoic acid receptor alpha (human), hRARA

organism-sequence


PR:P10276-1 retinoic acid receptor alpha isoform 1 (human), hRARA/iso:1

organism-modification


PR:000026078 retinoic acid receptor alpha isoform 1 phosphorylated 1 (human), hRARA/iso:1/Phos:1

organism-sequence


PR:P10276-2 retinoic acid receptor alpha isoform Alpha-2 (human), hRARA/iso:Alpha-2

organism-sequence


PR:P10276-3 retinoic acid receptor alpha isoform hAlpha-1-deltaBC (human), hRARA/iso:hAlpha-1-deltaBC

organism-modification


PR:000045664 retinoic acid receptor alpha phosphorylated 1 (human), hRARA/Phos:1

organism-modification


PR:000064719 retinoic acid receptor alpha sumoylated 1 (human), hRARA/Sumo:1

organism-modification


PR:000064730 retinoic acid receptor alpha phosphorylated and sumoylated 1 (human), hRARA/PhosSumo:1

organism-gene


PR:P11416 retinoic acid receptor alpha (mouse), mRARA
Yes
organism-sequence


PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse), mRARA/iso:1
Yes
organism-modification


PR:000026077 retinoic acid receptor alpha isoform 1 phosphorylated 1 (mouse), mRARA/iso:1/Phos:1

organism-sequence


PR:P11416-2 retinoic acid receptor alpha isoform Alpha-2 (mouse), mRARA/iso:Alpha-2

organism-gene


PR:Q90271 retinoic acid receptor alpha-A (zebrafish), z-RARA

organism-gene


PR:Q90966 retinoic acid receptor alpha (chicken), chick-RARA

organism-sequence


PR:Q90966-1 retinoic acid receptor alpha isoform Alpha-1 (chicken), chick-RARA/iso:Alpha-1

organism-sequence


PR:Q90966-2 retinoic acid receptor alpha isoform Alpha-2 (chicken), chick-RARA/iso:Alpha-2

sequence


PR:000022009 retinoic acid receptor alpha isoform 1, RARA/iso:1

organism-sequence


PR:P10276-1 retinoic acid receptor alpha isoform 1 (human), hRARA/iso:1

organism-modification


PR:000026078 retinoic acid receptor alpha isoform 1 phosphorylated 1 (human), hRARA/iso:1/Phos:1

organism-sequence


PR:P11416-1 retinoic acid receptor alpha isoform 1 (mouse), mRARA/iso:1
Yes
organism-modification


PR:000026077 retinoic acid receptor alpha isoform 1 phosphorylated 1 (mouse), mRARA/iso:1/Phos:1

modification


PR:000026076 retinoic acid receptor alpha isoform 1 phosphorylated 1, RARA/iso:1/Phos:1

organism-modification


PR:000026077 retinoic acid receptor alpha isoform 1 phosphorylated 1 (mouse), mRARA/iso:1/Phos:1

organism-modification


PR:000026078 retinoic acid receptor alpha isoform 1 phosphorylated 1 (human), hRARA/iso:1/Phos:1

sequence


PR:000022010 retinoic acid receptor alpha isoform 2, RARA/iso:2

organism-sequence


PR:P10276-2 retinoic acid receptor alpha isoform Alpha-2 (human), hRARA/iso:Alpha-2

organism-sequence


PR:P11416-2 retinoic acid receptor alpha isoform Alpha-2 (mouse), mRARA/iso:Alpha-2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P11416 mRARA
Nr1b1 | Rara | nuclear receptor subfamily 1 group B member 1 (mouse) | RAR-alpha (mouse)
"A retinoic acid receptor alpha that is encoded in the genome of mouse." [OMA:P11416, PRO:DNx]		 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II PMID:7566114
GO:0001657 ureteric bud development PMID:12195422
GO:0007283 spermatogenesis MGI:61760; PMID:8394014
GO:0008284 positive regulation of cell population proliferation PMID:18026104
GO:0010629 negative regulation of gene expression PMID:18026104
GO:0030852 regulation of granulocyte differentiation PMID:11222375
GO:0032526 response to retinoic acid PMID:11222375
GO:0045944 positive regulation of transcription by RNA polymerase II PMID:7823919
GO:0045944 positive regulation of transcription by RNA polymerase II PMID:7823919
GO:0055012 ventricular cardiac muscle cell differentiation PMID:9428411
enablesGO:0043565 sequence-specific DNA binding PMID:7823919
PR:P11416-1 mRARA/iso:1
mRARalpha1
"A retinoic acid receptor alpha isoform 1 that is encoded in the genome of mouse." [PRO:HJD]		 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II PMID:8152920
GO:0006355 regulation of DNA-templated transcription PMID:12101409
GO:0006355 regulation of DNA-templated transcription PMID:12101409
GO:0045892 negative regulation of DNA-templated transcription PMID:11641275
GO:0045947 negative regulation of translational initiation MGI:3803427; PMID:18495661
enablesGO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding MGI:3053708; PMID:1655807
GO:0003677 DNA binding PMID:15528198
GO:0003677 DNA binding PMID:15528198
GO:0003700 DNA-binding transcription factor activity PMID:8152920
GO:0003700 DNA-binding transcription factor activity PMID:8152920
GO:0004879 nuclear receptor activity PMID:15322135
GO:0004879 nuclear receptor activity PMID:15322135
GO:0005515 protein binding PMID:10531331
GO:0005515 protein binding PMID:10531331
GO:0043565 sequence-specific DNA binding PMID:17928865
located_inGO:0005634 nucleus with CHEBI:15367 PMID:12079996
GO:0005737 cytoplasm PMID:12079996
GO:0030425 dendrite MGI:3803427; PMID:18495661
GO:0043025 neuronal cell body MGI:3803427; PMID:18495661