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Protein Ontology report - ribosomal protein S6 kinase alpha-6
PR:000014287 - http://purl.obolibrary.org/obo/PR_000014287
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000014287   
  PRO nameribosomal protein S6 kinase alpha-6 
  Synonyms
PRO-Short-label: EXACT:RPS6KA6
Gene-based: RELATED:RSK4
Other: EXACT:90 kDa ribosomal protein S6 kinase 6 | p90-RSK 6 | p90RSK6 | pp90RSK4 | ribosomal S6 kinase 4 | RSK-4 | S6K-alpha-6
  Definition"A ribosomal protein S6 kinase alpha that is a translation product of the human RPS6KA6 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000029187 ribosomal protein S6 kinase alpha
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1530
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000014287 ribosomal protein S6 kinase alpha-6, RPS6KA6

organism-gene


PR:Q6PFQ0 ribosomal protein S6 kinase alpha-6 (zebrafish), z-RPS6KA6

organism-gene


PR:Q7TPS0 ribosomal protein S6 kinase alpha-6 (mouse), mRPS6KA6

organism-sequence


PR:E9QK39 ribosomal protein S6 kinase alpha-6 isoform m4 (mouse), mRPS6KA6/iso:m4

organism-modification


PR:000049868 ribosomal protein S6 kinase alpha-6 isoform m4 phosphorylated 1 (mouse), mRPS6KA6/iso:m4/Phos:1

organism-sequence


PR:Q7TPS0-1 ribosomal protein S6 kinase alpha-6 isoform m1 (mouse), mRPS6KA6/iso:m1

organism-sequence


PR:Q7TPS0-2 ribosomal protein S6 kinase alpha-6 isoform m2 (mouse), mRPS6KA6/iso:m2

organism-sequence


PR:Q7TPS0-3 ribosomal protein S6 kinase alpha-6 isoform m3 (mouse), mRPS6KA6/iso:m3

organism-gene


PR:Q9UK32 ribosomal protein S6 kinase alpha-6 (human), hRPS6KA6

organism-sequence


PR:Q9UK32-1 ribosomal protein S6 kinase alpha-6 isoform h1 (human), hRPS6KA6/iso:h1

organism-sequence


PR:Q9UK32-2 ribosomal protein S6 kinase alpha-6 isoform h2 (human), hRPS6KA6/iso:h2

organism-modification


PR:000049133 ribosomal protein S6 kinase alpha-6 phosphorylated 1 (human), hRPS6KA6/Phos:1
Yes
organism-modification


PR:000049860 ribosomal protein S6 kinase alpha-6 unphosphorylated 1 (human), hRPS6KA6/UnPhos:1

organism-modification


PR:000063107 ribosomal protein S6 kinase alpha-6 phosphorylated 2 (human), hRPS6KA6/Phos:2

organism-modification


PR:000063168 ribosomal protein S6 kinase alpha-6 phosphorylated 3 (human), hRPS6KA6/Phos:3

organism-modification


PR:000064014 ribosomal protein S6 kinase alpha-6 phosphorylated 4 (human), hRPS6KA6/Phos:4

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000049133 hRPS6KA6/Phos:1
UniProtKB:Q9UK32, Ser-232/Ser-372/Ser-389, MOD:00046|Thr-581, MOD:00047 | UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389, MOD:00046|Thr-581, MOD:00047
"A ribosomal protein S6 kinase alpha-6 (human) that has been phosphorylated on residues at positions equivalent to Ser-232, Ser-372, Ser-389, and Thr-581 of the amino acid sequence represented by UniProtKB:Q9UK32-1. Example: UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389, MOD:00046|Thr-581, MOD:00047." [PMID:15632195, PRO:DNx, PRO:KER, Reactome:R-HSA-444293]		 enablesincreased GO:0004674 protein serine/threonine kinase activity relative to PR:000049860 hRPS6KA6/UnPhos:1 PMID:15632195