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Protein Ontology report - STE20/SPS1-related proline-alanine-rich protein kinase
PR:000015756 - http://purl.obolibrary.org/obo/PR_000015756
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000015756   
  PRO nameSTE20/SPS1-related proline-alanine-rich protein kinase 
  Synonyms
PRO-Short-label: EXACT:STK39
Gene-based: RELATED:PASK | SPAK
Other: EXACT:DCHT | serine/threonine-protein kinase 39 | Ste-20-related kinase
  Definition"A protein that is a translation product of the human STK39 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2224
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000015756 STE20/SPS1-related proline-alanine-rich protein kinase, STK39

organism-gene


PR:O88506 STE20/SPS1-related proline-alanine-rich protein kinase (rat), rSTK39

organism-gene


PR:Q12701 serine/threonine-protein kinase ksg1 (Schizosaccharomyces pombe 972h-), Spom972h-STK39

organism-gene


PR:Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase (human), hSTK39

organism-sequence


PR:Q9UEW8-1 STE20/SPS1-related proline-alanine-rich protein kinase isoform h1 (human), hSTK39/iso:h1

organism-sequence


PR:Q9UEW8-2 STE20/SPS1-related proline-alanine-rich protein kinase isoform h2 (human), hSTK39/iso:h2

organism-modification


PR:000077909 STE20/SPS1-related proline-alanine-rich protein kinase methylated 1 (human), hSTK39/Me:1

organism-gene


PR:Q9Z1W9 STE20/SPS1-related proline-alanine-rich protein kinase (mouse), mSTK39

organism-sequence


PR:000044370 STE20/SPS1-related proline-alanine-rich protein kinase isoform 3 (mouse), mSTK39/iso:3
Yes
organism-sequence


PR:G1JLS7 STE20/SPS1-related proline-alanine-rich protein kinase isoform 2 (mouse), mSTK39/iso:2
Yes
organism-sequence


PR:Q9Z1W9-1 STE20/SPS1-related proline-alanine-rich protein kinase isoform 1 (mouse), mSTK39/iso:1
Yes
modification


PR:000021589 STE20/SPS1-related proline-alanine-rich protein kinase, initiator methionine removed form, STK39/InitMet-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044370 mSTK39/iso:3
UniProtKB:Q9Z1W9, 115-556 | SPAK2
"A STE20/SPS1-related proline-alanine-rich protein kinase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z1W9, 115-556." [PMID:21907141, PMID:24133122, PRO:HJD]		 enablesGO:0005515 protein binding with PR:P55014-4 MGI:5538439; PMID:24133122
PR:G1JLS7 mSTK39/iso:2
Kidney-specific SPAK | KS-SPAK
"A STE20/SPS1-related proline-alanine-rich protein kinase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G1JLS7." [PMID:21907141, PMID:24133122, PRO:HJD]		 acts_upstream_of_or_withinGO:0001933 negative regulation of protein phosphorylation MGI:5292405; PMID:21907141
GO:1901380 negative regulation of potassium ion transmembrane transport MGI:5538439; PMID:24133122
enablesGO:0005515 protein binding with PR:P55014-4 MGI:5538439; PMID:24133122
PR:Q9Z1W9-1 mSTK39/iso:1

"A STE20/SPS1-related proline-alanine-rich protein kinase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z1W9-1." [PMID:10980603, PRO:HJD]		 enablesGO:0004672 protein kinase activity MGI:5292405; PMID:21907141
GO:0005515 protein binding MGI:5538439; PMID:24133122