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Protein Ontology report - tumor necrosis factor proteolytic cleavage product
PR:000018285 - http://purl.obolibrary.org/obo/PR_000018285
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000018285   
  PRO nametumor necrosis factor proteolytic cleavage product 
  Synonyms
PRO-Short-label: EXACT:TNF/ClvPrd
  Definition"A tumor necrosis factor that has been processed by proteolytic cleavage." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000000134 tumor necrosis factor
PR:000018264 proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000018285 tumor necrosis factor proteolytic cleavage product, TNF/ClvPrd

modification


PR:000000604 tumor necrosis factor isoform 1 cleaved 1, TNF/iso:1/Clv:1

organism-modification


PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human), hTNF/iso:1/Clv:1
Yes
organism-modification


PR:000036505 tumor necrosis factor isoform 1 cleaved 1 (mouse), mTNF/iso:1/Clv:1
Yes
modification


PR:000000605 tumor necrosis factor isoform 1 cleaved 2, TNF/iso:1/Clv:2

organism-modification


PR:000036506 tumor necrosis factor isoform 1 cleaved 2 (mouse), mTNF/iso:1/Clv:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036504 hTNF/iso:1/Clv:1
UniProtKB:P01375-1, 77-233 | PRO_0000034424
"A tumor necrosis factor isoform 1 cleaved 1 in human. UniProtKB:P01375-1, 77-233." [PMID:14512626, PMID:3856324, PRO:CNA]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:3856324
enablesGO:0005164 tumor necrosis factor receptor binding with PR:P19438 CD120a (human) PMID:14512626
GO:0042802 identical protein binding PMID:14512626
PR:000036505 mTNF/iso:1/Clv:1
UniProtKB:P06804-1, 80-235 | PRO_0000034436
"A tumor necrosis factor isoform 1 cleaved 1 in mouse. UniProtKB:P06804-1, 80-235." [PMID:10089307, PMID:9305915, PRO:CNA]		 acts_upstream_of_or_withinGO:0006355 regulation of DNA-templated transcription PMID:9305915
located_inGO:0005615 extracellular space PMID:10089307
PR:000036506 mTNF/iso:1/Clv:2
UniProtKB:P06804-1, 70-235
"A tumor necrosis factor isoform 1 cleaved 2 in mouse. UniProtKB:P06804-1, 70-235." [PMID:2777790, PRO:CNA]		 enablesNOT GO:0005125 cytokine activity PMID:2777790
located_inGO:0005576 extracellular region PMID:2777790