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Protein Ontology report - sonic hedgehog protein proteolytic cleavage product
PR:000021468 - http://purl.obolibrary.org/obo/PR_000021468
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000021468   
  PRO namesonic hedgehog protein proteolytic cleavage product 
  Synonyms
PRO-Short-label: EXACT:SHH/ClvPrd
  Definition"A sonic hedgehog protein that has been processed by proteolytic cleavage." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000014841 sonic hedgehog protein
PR:000018264 proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification3                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000021468 sonic hedgehog protein proteolytic cleavage product, SHH/ClvPrd

modification


PR:000037273 sonic hedgehog protein N-product, SHH/Clv:Nter

organism-modification


PR:000037269 sonic hedgehog protein N-product dually lipidated 1 (mouse), mSHH/Clv:Nter/2*Lipid:1
Yes
organism-modification


PR:000037274 sonic hedgehog protein N-product dually lipidated 1 (human), hSHH/Clv:Nter/2*Lipid:1

modification


PR:000037275 sonic hedgehog protein C-product, SHH/Clv:Cter

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037269 mSHH/Clv:Nter/2*Lipid:1
UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314
"A sonic hedgehog protein N-product in mouse that has been further modified on the N-terminal Cys residue by palmitoylation and the C-terminal Gly residue by cholesterylation. UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314." [PMID:15075292, PMID:8824192, PRO:KRC]		 acts_upstream_of_or_withinGO:0007224 smoothened signaling pathway MGI:3039193; PMID:15075292
GO:0009952 anterior/posterior pattern specification MGI:2135419; PMID:11389830
GO:0030326 embryonic limb morphogenesis MGI:2135419; PMID:11389830
GO:0042733 embryonic digit morphogenesis MGI:3039193; PMID:15075292