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Protein Ontology report - interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form
PR:000021971 -
http://purl.obolibrary.org/obo/PR_000021971
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000021971
PRO name
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form
Synonyms
PRO-Short-label
:
EXACT:
IRAK1/iso:1/PhosRes+
Definition
"An interleukin-1 receptor-associated kinase 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
PRO Category
modification
Parent
PR:000021973
interleukin-1 receptor-associated kinase 1 isoform 1
PR:000037070
phosphoprotein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
4
Organism-Modification
5
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000021971
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form, IRAK1/iso:1/PhosRes+
modification
PR:000021975
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1, IRAK1/iso:1/Phos:1
organism-modification
PR:000027178
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (mouse), mIRAK1/iso:1/Phos:1
Yes
organism-modification
PR:000027494
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human), hIRAK1/iso:1/Phos:1
Yes
Yes
modification
PR:000021977
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3, IRAK1/iso:1/Phos:3
organism-modification
PR:000027492
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human), hIRAK1/iso:1/Phos:3
Yes
modification
PR:000021978
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4, IRAK1/iso:1/Phos:4
organism-modification
PR:000027493
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human), hIRAK1/iso:1/Phos:4
Yes
organism-modification
PR:000061935
interleukin-1 receptor-associated kinase 1 isoform 1 phosphoserine and phosphothreonine form (human), hIRAK1/iso:1/pSerThr+
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IRAK1/iso:1/PhosRes+
forms found in complexes
IRAK1/iso:1/PhosRes+
Component
Complexes
PR:000027178
mIRAK1/iso:1/Phos:1
PR:000027221
pIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000027494
hIRAK1/iso:1/Phos:1
PR:000027495
pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027492
hIRAK1/iso:1/Phos:3
UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047 | pp-IRAK1 (human)
"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA]
acts_upstream_of_or_within
GO:0070498
interleukin-1-mediated signaling pathway
PMID:14625308
enables
GO:0004674
protein serine/threonine kinase activity
PMID:14625308
PR:000027493
hIRAK1/iso:1/Phos:4
UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046 | hp-IRAK1 (human)
"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]
acts_upstream_of_or_within
GO:0070498
interleukin-1-mediated signaling pathway
PMID:14625308
enables
GO:0004674
protein serine/threonine kinase activity
PMID:14625308
NOT
GO:0005515
protein binding
with
PR:Q99836
hMYD88
PMID:14625308
NOT
GO:0005515
protein binding
PMID:14625308
PR:000027494
hIRAK1/iso:1/Phos:1
UniProtKB:P51617-1, Thr-209, MOD:00047
"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P51617-1, Thr-209, MOD:00047." [PRO:DNx, UniProtKB:P51617]
enables
GO:0005515
protein binding
with
PR:Q9NWZ3
hIRAK4
PMID:11960013
GO:0016301
kinase activity
PMID:11960013
