back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4
PR:000021978 - http://purl.obolibrary.org/obo/PR_000021978
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000021978   
  PRO nameinterleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 
  Synonyms
PRO-Short-label: EXACT:IRAK1/iso:1/Phos:4
Other: EXACT:hp-IRAK1 | interleukin-1 receptor-associated kinase 1 hyperphosphorylated
  Definition"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation occurs by interleukin-1 receptor-associated kinase 4 (IRAK-4) and extensively autophosphorylated in the Pro-, Ser-, and Thr-rich ProST region between the N-terminal death domain and kinase domain. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA, PRO:DAN] 
  PRO Categorymodification 
  ParentPR:000021971 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000021978 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4, IRAK1/iso:1/Phos:4

organism-modification


PR:000027493 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human), hIRAK1/iso:1/Phos:4
Yes
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027493 hIRAK1/iso:1/Phos:4
UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046 | hp-IRAK1 (human)
"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]		 acts_upstream_of_or_withinGO:0070498 interleukin-1-mediated signaling pathway PMID:14625308
enablesGO:0004674 protein serine/threonine kinase activity PMID:14625308
NOT GO:0005515 protein binding with PR:Q99836 hMYD88 PMID:14625308
NOT GO:0005515 protein binding PMID:14625308