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Protein Ontology report - myeloid differentiation primary response protein MyD88 isoform 2
PR:000024846 - http://purl.obolibrary.org/obo/PR_000024846
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000024846   
  PRO namemyeloid differentiation primary response protein MyD88 isoform 2 
  Synonyms
PRO-Short-label: EXACT:MYD88/iso:2
Other: EXACT:MyD88s
  Definition"A myeloid differentiation primary response protein MyD88 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22366-2 or a 1:1 ortholog thereof." [PMID:11909531, PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000001740 myeloid differentiation primary response protein MyD88
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000024846 myeloid differentiation primary response protein MyD88 isoform 2, MYD88/iso:2


organism-sequence



PR:P22366-2 myeloid differentiation primary response protein MyD88 isoform 2 (mouse), mMYD88/iso:2

Yes

Yes
organism-sequence



PR:Q99836-2 myeloid differentiation primary response protein MyD88 isoform 2 (human), hMYD88/iso:2


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MYD88/iso:2 forms found in complexes   

MYD88/iso:2 Component
Complexes
PR:P22366ZDASHZ2 mMYD88/iso:2 PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P22366-2 mMYD88/iso:2

"A myeloid differentiation primary response protein MyD88 isoform 2 that is encoded in the genome of mouse." [PMID:11909531, PRO:CNA]
acts_upstream_of_or_withinGO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway PMID:12538665