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Protein Ontology report - isocitrate dehydrogenase [NADP] isoform 1 phosphorylated 1
PR:000025141 -
http://purl.obolibrary.org/obo/PR_000025141
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000025141
PRO name
isocitrate dehydrogenase [NADP] isoform 1 phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
icd/iso:1/Phos:1
Other
:
EXACT:
isocitrate dehydrogenase inactive | isocitrate dehydrogenase phosphate | isocitrate dehydrogenase-P
Definition
"An isocitrate dehydrogenase [NADP] isoform 1 that has been phosphorylated by aceK on a Ser residue involved in substrate binding, leading to inactivation of isocitrate dehydrogenase. Example:
UniProtKB:P08200-1
, Ser-113,
MOD:00046
." [
EcoCyc:ISOCITHASE
-P,
PMID:3112144
]
PRO Category
modification
Parent
PR:000025138
isocitrate dehydrogenase [NADP] isoform 1
PR:000037070
phosphoprotein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000025141
isocitrate dehydrogenase [NADP] isoform 1 phosphorylated 1, icd/iso:1/Phos:1
organism-modification
PR:000036731
isocitrate dehydrogenase [NADP] isoform 1 phosphorylated 1 (Escherichia coli K-12), Ec-icd/iso:1/Phos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036731
Ec-icd/iso:1/Phos:1
UniProtKB:P08200-1, Ser-113, MOD:00046
"An isocitrate dehydrogenase [NADP] isoform 1 phosphorylated 1 in Escherichia coli K-12. UniProtKB:P08200-1, Ser-113, MOD:00046." [EcoCyc:ISOCITHASE-P, PRO:CNA]
acts_upstream_of_or_within
GO:0006099
tricarboxylic acid cycle
EcoCyc:ISOCITHASE-P
