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Protein Ontology report - interleukin-6 receptor subunit alpha proteolytic cleavage product

PR:000025429 - http://purl.obolibrary.org/obo/PR_000025429

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000025429

PRO name

interleukin-6 receptor subunit alpha proteolytic cleavage product

Synonyms

PRO-Short-label:

EXACT:

IL6R/ClvPrd

Definition

"An interleukin-6 receptor subunit alpha that has been processed by proteolytic cleavage." [PRO:DNx]

PRO Category

modification

Parent

PR:000001394 interleukin-6 receptor subunit alpha
PR:000018264 proteolytic cleavage product

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	2	Organism-Modification	1

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

modification

PR:000025429 interleukin-6 receptor subunit alpha proteolytic cleavage product, IL6R/ClvPrd

modification

PR:000001798 interleukin-6 receptor subunit alpha isoform 1 soluble form, IL6R/iso:1/Clv:soluble

organism-modification

PR:000044514 interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse), mIL6R/iso:1/Clv:soluble

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000044514 mIL6R/iso:1/Clv:soluble "An interleukin-6 receptor subunit alpha isoform 1 soluble form in mouse." [PRO:DNx]	acts_upstream_of_or_within	GO:0070102 interleukin-6-mediated signaling pathway	PMID:8477802
	enables	GO:0004915 interleukin-6 receptor activity	PMID:8477802
	enables	GO:0019981 interleukin-6 binding	PMID:8477802
	located_in	GO:0005615 extracellular space	PMID:8477802