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RACE-PRO
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Protein Ontology report - mediator of RNA polymerase II transcription subunit 28 isoform 1
PR:000025609 -
http://purl.obolibrary.org/obo/PR_000025609
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000025609
PRO name
mediator of RNA polymerase II transcription subunit 28 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
MED28/iso:1
Definition
"A mediator of RNA polymerase II transcription subunit 28 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q9H204-1
or a 1:1 ortholog thereof." [PRO:JAN]
PRO Category
sequence
Parent
PR:000010300
mediator of RNA polymerase II transcription subunit 28
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000025609
mediator of RNA polymerase II transcription subunit 28 isoform 1, MED28/iso:1
organism-sequence
PR:Q920D3-1
mediator of RNA polymerase II transcription subunit 28 isoform 1 (mouse), mMED28/iso:1
Yes
Yes
organism-sequence
PR:Q9H204-1
mediator of RNA polymerase II transcription subunit 28 isoform 1 (human), hMED28/iso:1
organism-modification
PR:000025633
mediator of RNA polymerase II transcription subunit 28 isoform 1 phosphorylated 1 (human), hMED28/iso:1/Phos:1
Yes
modification
PR:000025611
mediator of RNA polymerase II transcription subunit 28 isoform 1 phosphorylated 1, MED28/iso:1/Phos:1
organism-modification
PR:000025633
mediator of RNA polymerase II transcription subunit 28 isoform 1 phosphorylated 1 (human), hMED28/iso:1/Phos:1
Yes
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MED28/iso:1
forms found in complexes
MED28/iso:1
Component
Complexes
PR:Q920D3ZDASHZ1
mMED28/iso:1
PR:000028902
mediator complex, MED26-containing (mouse)
PR:000028957
mediator complex, CDK8-containing (mouse)
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000025633
hMED28/iso:1/Phos:1
UniProtKB:Q9H204-1, Tyr-64, MOD:00048
"A mediator of RNA polymerase II transcription subunit 28 isoform 1 phosphorylated 1 in human. UniProtKB:Q9H204-1, Tyr-64, MOD:00048." [PMID:16899217, PRO:JAN]
enables
GO:0005515
protein binding
with
PR:P62993
adapter protein GRB2 (human)
PMID:16899217
PR:Q920D3-1
mMED28/iso:1
"A mediator of RNA polymerase II transcription subunit 28 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]
located_in
GO:0016592
mediator complex
MGI:4462751
;
PMID:20508642